Hydroxyurea and Amoxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydroxyurea (hydroxyurea) and Amoxil (amoxicillin). Common drug interactions include fall among females and acute chest syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Hydroxyurea and Amoxil. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Amoxil?

Amoxil has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 3,641 Amoxil users. Check the latest studies of Amoxil.



On Jul, 15, 2026

18 people who take Hydroxyurea and Amoxil together, and have interactions are studied.

Hydroxyurea and Amoxil drug interactions.

What are the common drug interactions of Hydroxyurea and Amoxil, by gender? *:

female:

  1. Fall
  2. Hip fracture
  3. Humerus fracture (injury to the upper arm bone)

male:

  1. Acute chest syndrome (acute chest pain, fever and difficulty breathing)
  2. Hepatotoxicity (chemical-driven liver damage)
  3. Transaminases increased
  4. Osteonecrosis (death of bone)
  5. Abdominal pain
  6. Angiopathy (generic term for a disease of the blood vessels)
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  9. Hyperbilirubinaemia (excess of bilirubin in the blood)
  10. Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the common drug interactions of Hydroxyurea and Amoxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Hypoglycaemia (deficiency of glucose in the bloodstream)
  2. Transaminases increased
  3. Osteonecrosis (death of bone)
  4. Abdominal pain
  5. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  6. Hepatotoxicity (chemical-driven liver damage)
  7. Hyperbilirubinaemia (excess of bilirubin in the blood)

20-29:

  1. Acute chest syndrome (acute chest pain, fever and difficulty breathing)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Fall
  2. Hip fracture
  3. Humerus fracture (injury to the upper arm bone)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 6 people, 33.33%
  2. Constipation: 6 people, 33.33%
  3. Asplenia (absence of normal spleen function and is associated with some serious infection risks): 4 people, 22.22%
  4. Iron Overload: 3 people, 16.67%
  5. Anaemia (lack of blood): 3 people, 16.67%
  6. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 16.67%
  7. Acne (skin problems that cause pimples): 3 people, 16.67%
  8. Itching: 3 people, 16.67%
  9. Nausea (feeling of having an urge to vomit): 3 people, 16.67%
  10. Rickets (softening of bones): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and Amoxil?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydroxyurea and Amoxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amoxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyurea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea and amoxicillin (the active ingredients of Hydroxyurea and Amoxil, respectively), and Hydroxyurea and Amoxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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