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Ibuprofen and Pegintron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ibuprofen (ibuprofen) and Pegintron (peginterferon alfa-2b). Common drug interactions include oropharyngeal pain among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Ibuprofen and Pegintron. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Pegintron?

Pegintron has active ingredients of peginterferon alfa-2b. It is often used in hepatitis c. eHealthMe is studying from 10,326 Pegintron users. Check the latest studies of Pegintron.

On Aug, 06, 2026

76 people who take Ibuprofen and Pegintron together, and have interactions are studied.

Ibuprofen and Pegintron drug interactions.

What are the common drug interactions of Ibuprofen and Pegintron, by gender? *:

female:

  1. Oropharyngeal pain
  2. Palpitations (feelings or sensations that your heart is pounding or racing)
  3. Productive cough
  4. Skin atrophy (wasting of skin)
  5. Weight decreased
  6. Abscess soft tissue (soft tissue abscesses)
  7. Comminuted fracture (bone has broken into several pieces)
  8. Dysstasia (difficulty in standing)
  9. Fall
  10. Femur fracture

male:

  1. Fatigue (feeling of tiredness)
  2. Pyrexia (fever)
  3. Weight decreased
  4. Chills (felling of cold)
  5. Infection
  6. White blood cell count decreased
  7. Cough
  8. Rhinorrhoea (watery mucus discharge from the nose)
  9. Decreased appetite
  10. Haemoglobin decreased

What are the common drug interactions of Ibuprofen and Pegintron, by age (0-1 to 60+)? *:

0-1:

  1. Abdominal pain
  2. Candida nappy rash (fungal rash)
  3. Conjunctivitis viral (infection of conjunctiva by virus)
  4. Constipation
  5. Cough
  6. Croup infectious (a loud cough that resembles the barking of a seal and difficulty breathing can transfer to other)
  7. Decreased activity
  8. Decreased appetite
  9. Dermatitis diaper (diaper rash is a common form of inflamed skin)
  10. Diarrhoea

2-9:

  1. Rash
  2. Urticaria (rash of round, red welts on the skin that itch intensely)

10-19:

  1. Fatigue (feeling of tiredness)
  2. Alopecia (absence of hair from areas of the body)
  3. Nausea (feeling of having an urge to vomit)
  4. Pyrexia (fever)
  5. Weight decreased
  6. White blood cell count decreased

20-29:

  1. Activated partial thromboplastin time prolonged
  2. Colonic polyp (extra part of colon tissue grow in intestine)
  3. Dry mouth
  4. Duodenal polyp (duodenal epithelial tumours)
  5. Fall
  6. Feeling cold
  7. Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)
  8. Haemoglobin decreased
  9. Infection
  10. Injection site bruising

30-39:

  1. Dyspnoea (difficult or laboured respiration)
  2. Homicide (human killing another human)
  3. Injection site erythema (redness at injection site)
  4. Oropharyngeal pain
  5. Pharyngeal erythema (pharyngeal redness)
  6. Throat irritation

40-49:

  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Pyrexia (fever)
  4. Influenza like illness
  5. Chills (felling of cold)
  6. Insomnia (sleeplessness)
  7. White blood cell count decreased
  8. Decreased appetite
  9. Dry mouth
  10. Vomiting

50-59:

  1. Dry skin
  2. Injection site erythema (redness at injection site)
  3. Injection site pruritus (severe itching at injection site)
  4. Injection site reaction
  5. Insomnia (sleeplessness)
  6. Lethargy (tiredness)
  7. Lymphatic disorder (disease of lymphatic system)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Mobility decreased (ability to move is reduced)
  10. Tongue ulceration (ulcers on tongue)

60+:

  1. Pain in extremity
  2. Depression
  3. Abdominal pain upper
  4. Abscess soft tissue (soft tissue abscesses)
  5. Anaemia (lack of blood)
  6. Anxiety
  7. Arthralgia (joint pain)
  8. Blood triglycerides increased
  9. Bone pain
  10. Chest pain

What are the existing conditions these people have? *

  1. Depression: 6 people, 7.89%
  2. Headache (pain in head): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and Pegintron?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ibuprofen and Pegintron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pegintron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibuprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pegintron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and peginterferon alfa-2b (the active ingredients of Ibuprofen and Pegintron, respectively), and Ibuprofen and Pegintron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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