Implanon and Lamictal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Implanon (etonogestrel) and Lamictal (lamotrigine). Common drug interactions include weight increased among females.
The phase IV clinical study analyzes what interactions people have when they take Implanon and Lamictal. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Implanon?
Implanon has active ingredients of etonogestrel. It is often used in birth control. eHealthMe is studying from 12,479 Implanon users. Check the latest studies of Implanon.
What is Lamictal?
Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,627 Lamictal users. Check the latest studies of Lamictal.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
34 people who take Implanon and Lamictal together, and have interactions are studied.

What are the common drug interactions of Implanon and Lamictal, by gender? *:
female:
- Weight increased
- Anxiety
- Weight decreased
- Abdominal pain lower
- Alanine aminotransferase increased
- Albumin urine present
- Compulsive shopping
- Cough
- Depression
- Dysplasia (enlargement of an organ or tissue)
male:
n/a
What are the common drug interactions of Implanon and Lamictal, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Medical device complication
- Anxiety
- Depressed level of consciousness
- Depression
- Feeling cold
- Insomnia (sleeplessness)
- Irritability
- Menstruation irregular
- Metrorrhagia (uterine bleeding at irregular intervals)
- Suicidal ideation
20-29:
- Suicidal ideation
- Vaginal haemorrhage (vaginal bleeding)
- Weight increased
- Abdominal pain lower
- Alanine aminotransferase increased
- Albumin urine present
- Anxiety
- Compulsive shopping
- Constipation
- Cough
30-39:
- Depression
- Mood swings (an extreme or rapid change in mood)
- Anxiety
40-49:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Drug abuse
- Feeling cold
- Headache (pain in head)
- Mood swings (an extreme or rapid change in mood)
- Overdose
- Premature menopause
- Tongue biting
- Weight increased
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Insomnia (sleeplessness): 4 people, 11.76%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 11.76%
- Wheezing (a high-pitched whistling sound made while you breath): 3 people, 8.82%
- Stress And Anxiety: 3 people, 8.82%
- Pelvic Pain: 3 people, 8.82%
- Panic Disorder: 3 people, 8.82%
- Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 3 people, 8.82%
- Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 8.82%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Implanon and Lamictal?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Implanon and Lamictal:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Implanon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lamictal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Implanon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lamictal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on etonogestrel and lamotrigine (the active ingredients of Implanon and Lamictal, respectively), and Implanon and Lamictal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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