Invanz and Ultram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Invanz (ertapenem sodium) and Ultram (tramadol hydrochloride). Common drug interactions include cardiac failure among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Invanz and Ultram. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Invanz?

Invanz has active ingredients of ertapenem sodium. It is often used in urinary tract infection. eHealthMe is studying from 3,961 Invanz users. Check the latest studies of Invanz.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.



On Aug, 05, 2026

15 people who take Invanz and Ultram together, and have interactions are studied.

Invanz and Ultram drug interactions.

What are the common drug interactions of Invanz and Ultram, by gender? *:

female:

  1. Cardiac failure
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Pyrexia (fever)
  4. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  5. Back pain
  6. Cellulitis (infection under the skin)
  7. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  8. Fear of disease
  9. Female genital tract fistula (passage in genital tract of female)
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

male:

  1. Diarrhoea
  2. Orchitis (inflammation of the testes)
  3. Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  6. Postoperative abscess
  7. Rectal haemorrhage (bleeding from anus)
  8. Renal failure (kidney dysfunction)
  9. Renal failure acute (rapid kidney dysfunction)
  10. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)

What are the common drug interactions of Invanz and Ultram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Fear of disease
  2. Injury
  3. Pulmonary embolism (blockage of the main artery of the lung)

40-49:

  1. Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
  2. Renal failure (kidney dysfunction)

50-59:

n/a

60+:

  1. Cardiac failure
  2. Diarrhoea
  3. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  4. Orchitis (inflammation of the testes)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  7. Postoperative abscess
  8. Pyrexia (fever)
  9. Renal failure acute (rapid kidney dysfunction)
  10. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 20.00%
  2. Nausea (feeling of having an urge to vomit): 3 people, 20.00%
  3. Constipation: 3 people, 20.00%
  4. Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 3 people, 20.00%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 13.33%
  6. High Blood Pressure: 2 people, 13.33%
  7. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 6.67%
  8. Gout (uric acid crystals building up in the body): 1 person, 6.67%
  9. Celiac Disease - Sprue (a disease of the small intestine): 1 person, 6.67%
  10. Cellulitis (infection under the skin): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Invanz and Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Invanz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Invanz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ultram and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ertapenem sodium and tramadol hydrochloride (the active ingredients of Invanz and Ultram, respectively), and Invanz and Ultram (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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