1. Home
  2. Analysis
  3. Isoniazid
  4. Advil

Isoniazid and Advil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoniazid (isoniazid) and Advil (ibuprofen). Common drug interactions include vomiting among females and respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Isoniazid and Advil. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

On Jul, 11, 2026

20 people who take Isoniazid and Advil together, and have interactions are studied.

Isoniazid and Advil drug interactions.

What are the common drug interactions of Isoniazid and Advil, by gender? *:

female:

  1. Vomiting
  2. Blood pressure fluctuation
  3. Gout (uric acid crystals building up in the body)
  4. Heart rate irregular
  5. Influenza
  6. Lower respiratory tract infection
  7. Peripheral swelling
  8. Heart rate decreased
  9. Hypotension (abnormally low blood pressure)
  10. Weight increased

male:

  1. Respiratory failure (inadequate gas exchange by the respiratory system)
  2. Abdominal distension
  3. Loss of consciousness
  4. Nausea (feeling of having an urge to vomit)
  5. Platelet count decreased
  6. Pneumonia
  7. Splenomegaly (enlargement of spleen)
  8. Vomiting
  9. Abdominal discomfort
  10. Acute hepatic failure

What are the common drug interactions of Isoniazid and Advil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal tenderness
  2. Haematuria present (presence of blood in urine due to trauma)
  3. Hepatitis (inflammation of the liver)
  4. Nausea (feeling of having an urge to vomit)
  5. Vomiting
  6. Weakness

20-29:

n/a

30-39:

  1. Sensation of heaviness
  2. Bone marrow failure
  3. Cholecystitis chronic (long lasting infection of gallbladder)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Diarrhoea
  6. Fear of disease
  7. Gallbladder disorder
  8. Injection site reaction
  9. Injury
  10. Liver disorder (liver diseases)

40-49:

  1. Abdominal pain
  2. Ammonia increased
  3. Liver disorder (liver diseases)
  4. Nausea (feeling of having an urge to vomit)
  5. Pneumonia
  6. Respiratory failure (inadequate gas exchange by the respiratory system)
  7. Vomiting
  8. Abdominal distension
  9. Alanine aminotransferase increased
  10. Aspartate aminotransferase increased

50-59:

  1. Vomiting
  2. Blood pressure fluctuation
  3. Gout (uric acid crystals building up in the body)
  4. Heart rate irregular
  5. Influenza
  6. Lower respiratory tract infection
  7. Peripheral swelling
  8. Heart rate decreased
  9. Hypotension (abnormally low blood pressure)
  10. Weight increased

60+:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Depression
  3. Eye swelling
  4. Foreign body sensation in eyes (feeling of something in eye)
  5. Gastric ulcer (stomach ulcer)
  6. Haemorrhage subcutaneous (bleeding from skin)
  7. Hydronephrosis (water inside the kidney)
  8. Platelet count decreased
  9. Pyelonephritis (inflammation of kidney caused by bacteria)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 55.00%
  2. High Blood Pressure: 7 people, 35.00%
  3. Hepatitis C: 4 people, 20.00%
  4. Oropharyngeal Pain: 2 people, 10.00%
  5. Nausea (feeling of having an urge to vomit): 2 people, 10.00%
  6. Multiple Myeloma (cancer of the plasma cells): 2 people, 10.00%
  7. Agitation (state of anxiety or nervous excitement): 2 people, 10.00%
  8. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 10.00%
  9. Influenza Like Illness: 2 people, 10.00%
  10. Diarrhea: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and Advil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isoniazid and Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isoniazid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Advil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on isoniazid and ibuprofen (the active ingredients of Isoniazid and Advil, respectively), and Isoniazid and Advil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.