Isosorbide mononitrate and Uloric drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide mononitrate (isosorbide mononitrate) and Uloric (febuxostat). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide mononitrate and Uloric. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Uloric?

Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.

On Jul, 15, 2026

85 people who take Isosorbide mononitrate and Uloric together, and have interactions are studied.

Isosorbide mononitrate and Uloric drug interactions.

What are the common drug interactions of Isosorbide Mononitrate and Uloric, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Death
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hospitalisation
Diarrhoea
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abscess (pus)
Abscess limb (limb infection)
Asthenia (weakness)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Contusion (a type of hematoma of tissue in which capillaries)
Drug ineffective
Haematoma (collection of blood outside the blood vessels)
Platelet count decreased
Acetabulum fracture (socket of the hip joint- fracture)
Cardiac failure
Dyspnoea (difficult or laboured respiration)
Fall

What are the common drug interactions of Isosorbide Mononitrate and Uloric, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Dyspepsia (indigestion)
Renal injury (kidney injury)
Death
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Abdominal discomfort
Diarrhoea

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Platelet count decreased
Renal injury (kidney injury)
Acetabulum fracture (socket of the hip joint- fracture)
Cardiac failure
Fall
Fractured ischium

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 23.53%
Diabetes: 15 people, 17.65%
High Blood Cholesterol: 15 people, 17.65%
Stable Angina (a constant chest pain): 14 people, 16.47%
Pain: 12 people, 14.12%
High Blood Pressure: 10 people, 11.76%
Infection: 9 people, 10.59%
Blood Pressure Abnormal: 8 people, 9.41%
Hyperkalemia (damage to or disease of the kidney): 8 people, 9.41%
Inflammation: 7 people, 8.24%

* Approximation only. Some reports may have incomplete information.

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