Ismo and Prednisone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ismo (isosorbide mononitrate) and Prednisone (prednisone). Common drug interactions include hyponatraemia among females and atrial flutter among males.

The phase IV clinical study analyzes what interactions people have when they take Ismo and Prednisone. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Ismo?

Ismo has active ingredients of isosorbide mononitrate. eHealthMe is studying from 982 Ismo users. Check the latest studies of Ismo.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

On Jul, 15, 2026

30 people who take Ismo and Prednisone together, and have interactions are studied.

What are the common drug interactions of Ismo and Prednisone, by gender? *:

female:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Injection site reaction
Lymphocyte count increased
Mucosal erosion (peeling off of mucous membrane)
Oesophagitis (inflammation of oesophagus)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash macular (small, flat red spots)
Skin swelling

male:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Gait disturbance
Pleural effusion (water on the lungs)
Pulmonary hilum mass (lung cancer)
Speech disorder
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Heart rate increased

What are the common drug interactions of Ismo and Prednisone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Lethargy (tiredness)
Oedema peripheral (superficial swelling)
Pleural effusion (water on the lungs)
Pulmonary hilum mass (lung cancer)
Speech disorder
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Heart rate increased
Multiple injuries
Alcohol abuse

60+:

Hypotension (abnormally low blood pressure)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Depressed level of consciousness
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Gamma-glutamyltransferase increased
Genital ulceration (ulcers on sex organ)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Injection site reaction
Lymphocyte count increased

What are the existing conditions these people have? *

Cardiac Failure: 4 people, 13.33%
The Flu (the flu is caused by an influenza virus): 3 people, 10.00%
Herpes Zoster: 3 people, 10.00%
Essential Hypertension (primary hypertension): 3 people, 10.00%
Myopathy (a muscular disease in which the muscle fibres do not function): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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