Keflex and Nexium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Keflex (cephalexin) and Nexium (esomeprazole magnesium). Common drug interactions include diarrhoea among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Keflex and Nexium. It is created by eHealthMe based on reports of 1,177 people who take the same drugs from the FDA, and is updated regularly.
What is Keflex?
Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,843 Keflex users. Check the latest studies of Keflex.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.
1,177 people who take Keflex and Nexium together, and have interactions are studied.

What are the common drug interactions of Keflex and Nexium, by gender? *
What are the common drug interactions of Keflex and Nexium, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Keflex and Nexium?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Keflex and Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Keflex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keflex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nexium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cephalexin and esomeprazole magnesium (the active ingredients of Keflex and Nexium, respectively), and Keflex and Nexium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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