Ketoprofen and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ketoprofen (ketoprofen) and Ambien (zolpidem tartrate). Common drug interactions include intervertebral disc degeneration among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Ketoprofen and Ambien. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Ketoprofen?

Ketoprofen has active ingredients of ketoprofen. It is often used in pain. eHealthMe is studying from 15,048 Ketoprofen users. Check the latest studies of Ketoprofen.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

83 people who take Ketoprofen and Ambien together, and have interactions are studied.

Ketoprofen and Ambien drug interactions.

What are the common drug interactions of Ketoprofen and Ambien, by gender? *:

female:

Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Pleural effusion (water on the lungs)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood creatinine increased
Breast cancer
Breast cancer metastatic

male:

Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardioactive drug level above therapeutic
Cold sweat
Compression fracture (fracture due to pressure caused by injury)
Fall
Heart rate irregular
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Neck pain
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

What are the common drug interactions of Ketoprofen and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Aortic valve incompetence
Blood cholesterol increased
Blood triglycerides increased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Chronic kidney disease
Confusion
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Electrolyte imbalance
Infection
Lung disorder (lung disease)

30-39:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Antisocial personality disorder
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depressed mood
Disturbance in attention
Dizziness

40-49:

Rash
Delirium (wild excitement)
Postoperative wound infection
Renal failure acute (rapid kidney dysfunction)
Staphylococcal infection (an infection with staphylococcus bacteria)
Alanine aminotransferase increased
Chest pain
Depression
Drug effect decreased
Hyperhidrosis (abnormally increased sweating)

50-59:

Compression fracture (fracture due to pressure caused by injury)
Constipation
Depression
Drug abuser
Drug ineffective
Facial pain
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Oedema peripheral (superficial swelling)
Palpitations (feelings or sensations that your heart is pounding or racing)
Panic attack

60+:

Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Blood creatinine increased
Breast cancer
Breast cancer metastatic
Cervix haemorrhage uterine (bleeding from cervix in birth canal)
Disability
Epicondylitis (tennis elbow)
Herpes zoster
Hypercholesterolaemia (high levels of cholesterol in the blood)

What are the existing conditions these people have? *

High Blood Pressure: 14 people, 16.87%
Depression: 12 people, 14.46%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 11 people, 13.25%
Anaemia (lack of blood): 11 people, 13.25%
Sleep Disorder: 8 people, 9.64%
Headache (pain in head): 6 people, 7.23%
Diabetes: 6 people, 7.23%

* Approximation only. Some reports may have incomplete information.

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