L-methylfolate and Lisinopril drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take L-methylfolate (folic acid) and Lisinopril (lisinopril). Common drug interactions include anxiety among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take L-methylfolate and Lisinopril. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is L-methylfolate?
L-methylfolate has active ingredients of folic acid. It is often used in depression. eHealthMe is studying from 619 L-methylfolate users. Check the latest studies of L-methylfolate.
What is Lisinopril?
Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,656 Lisinopril users. Check the latest studies of Lisinopril.
25 people who take L-methylfolate and Lisinopril together, and have interactions are studied.

What are the common drug interactions of L-Methylfolate and Lisinopril, by gender? *:
female:
- Anxiety
- Headache (pain in head)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Pain
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
- Drug ineffective
- Hyperhidrosis (abnormally increased sweating)
- Insomnia (sleeplessness)
- Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
male:
- Death
- Fall
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Fatigue (feeling of tiredness)
- Malaise (a feeling of general discomfort or uneasiness)
- Neuropathy peripheral (surface nerve damage)
- Oral pain
- Oxygen saturation decreased
- Pain
- Pyrexia (fever)
What are the common drug interactions of L-Methylfolate and Lisinopril, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)
40-49:
- Headache (pain in head)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Pain
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
- Bedridden
- Impaired work ability
50-59:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
60+:
- Anxiety
- Death
- Rash erythematous (redness of the skin)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Surgery
- Tardive dyskinesia (a disorder that involves involuntary movements)
- Apathy
- Confusional state
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 36.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 20.00%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 16.00%
- Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 12.00%
- Diabetes: 3 people, 12.00%
- Swelling: 2 people, 8.00%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 8.00%
- Pain: 2 people, 8.00%
- Immunodeficiency Common Variable: 2 people, 8.00%
- Hypersensitivity: 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take L-methylfolate and Lisinopril?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- L-methylfolate (619 reports)
- Lisinopril (358,656 reports)
Browse all drug interactions of L-methylfolate and Lisinopril:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of L-methylfolate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lisinopril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between L-methylfolate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lisinopril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
- Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on folic acid and lisinopril (the active ingredients of L-methylfolate and Lisinopril, respectively), and L-methylfolate and Lisinopril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Drug interactions of Lodine and Yasmin - 6 seconds ago
- Could Flomax cause Ischaemic Cardiomyopathy? - 14 seconds ago
- Drug interactions of Chantix and Rabeprazole - 33 seconds ago
- Drug interactions of Dopamine Hydrochloride and Sufentanil Citrate - 35 seconds ago
- Blopress and Heart Fibrillation for Women aged 60+ - 41 seconds ago
- Blopress and Atrial Flutter for Women aged 60+ - 41 seconds ago
- Blopress and Atrial Fibrillation for Women aged 60+ - 41 seconds ago
- Blopress and Auricular Fibrillation for Women aged 60+ - 42 seconds ago
- Blopress and A-Fib for Women aged 60+ - 42 seconds ago
- Blopress and Atrial Fibrillation/Flutter for Women aged 60+ - 42 seconds ago