Levaquin and Elidel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levaquin (levofloxacin) and Elidel (pimecrolimus). Common drug interactions include depression among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Levaquin and Elidel. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

What is Elidel?

Elidel has active ingredients of pimecrolimus. It is often used in eczema. eHealthMe is studying from 5,201 Elidel users. Check the latest studies of Elidel.

On Jul, 12, 2026

70 people who take Levaquin and Elidel together, and have interactions are studied.

What are the common drug interactions of Levaquin and Elidel, by gender? *:

female:

Depression
Hodgkin's disease (cancer originating from white blood cells)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Mucosal inflammation (infection of mucous membrane)
Anxiety
Dysphagia (a condition in which swallowing is difficult or painful)
Jugular vein thrombosis (clot in jugular vein)
Lymphadenopathy (disease or enlargement of lymph nodes)
Menstruation irregular
Renal cyst (kidney cyst)

male:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Decreased appetite
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Hodgkin's disease (cancer originating from white blood cells)
Intervertebral disc protrusion (spinal disc protrusion)
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
Neuroendocrine carcinoma (cancer tumour that arise from cells of the endocrine (hormonal) and nervous systems)
Pain
Scoliosis (a medical condition in which a person's spine is curved from side to side)

What are the common drug interactions of Levaquin and Elidel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Acute leukaemia (blood cancer)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Alopecia (absence of hair from areas of the body)
Anal fissure
Atelectasis (partial or complete collapse of the lung)
Blood pressure decreased
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Contusion (a type of hematoma of tissue in which capillaries)
Hyperglycaemia (high blood sugar)

10-19:

n/a

20-29:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholecystitis chronic (long lasting infection of gallbladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pulmonary embolism (blockage of the main artery of the lung)
Wheezing (a high-pitched whistling sound made while you breath)

30-39:

Hodgkin's disease (cancer originating from white blood cells)
Injury
Mucosal inflammation (infection of mucous membrane)
Fatigue (feeling of tiredness)
Abdominal hernia
Abdominal pain
Arthralgia (joint pain)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Dysphagia (a condition in which swallowing is difficult or painful)
Intervertebral disc degeneration (spinal disc degeneration)

40-49:

Fibromyalgia (a long-term condition which causes pain all over the body)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Autoimmune hepatitis
Cardiovascular disorder (heart diseases)
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

Renal failure acute (rapid kidney dysfunction)
Cataract (clouding of the lens inside the eye)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Erectile dysfunction
Gynaecomastia (enlargement of the gland tissue of the male breast)
Mitral valve incompetence (inefficient heart valve)
Palpitations (feelings or sensations that your heart is pounding or racing)
Prostatism (symptom complex resulting from compression or obstruction of the urethra, due most commonly to nodular hyperplasia of the prostate)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Tricuspid valve incompetence (inefficient heart valve)

60+:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Neutropenia (an abnormally low number of neutrophils)
Abdominal pain
Back pain
Diarrhoea
Fall
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Intervertebral disc degeneration (spinal disc degeneration)
Neck pain

What are the existing conditions these people have? *

Pain: 16 people, 22.86%
Hair Loss: 10 people, 14.29%
Laryngitis (inflammation of the larynx): 7 people, 10.00%
Irritable Bowel Syndrome: 7 people, 10.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 10.00%
Acne (skin problems that cause pimples): 7 people, 10.00%
Immunodeficiency Common Variable: 5 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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