Lexapro and Nolvadex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Nolvadex (tamoxifen citrate). Common drug interactions include pneumonia among females and asthma among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Nolvadex. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Nolvadex?

Nolvadex has active ingredients of tamoxifen citrate. It is often used in breast cancer. eHealthMe is studying from 5,506 Nolvadex users. Check the latest studies of Nolvadex.



On Jul, 18, 2026

30 people who take Lexapro and Nolvadex together, and have interactions are studied.

Lexapro and Nolvadex drug interactions.

What are the common drug interactions of Lexapro and Nolvadex, by gender? *:

female:

  1. Pneumonia
  2. Asthma
  3. Back pain
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Dyspnoea exertional (breathlessness or shortness of breath)
  6. Metastases to bone (cancer spreads to bone)
  7. Oral infection
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Pain in extremity

male:

  1. Asthma
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  4. Arthralgia (joint pain)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Asthenia (weakness)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Atrioventricular block first degree (heart block first degree)
  9. Back pain
  10. Balance disorder

What are the common drug interactions of Lexapro and Nolvadex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Hyperhidrosis (abnormally increased sweating)
  2. Memory impairment
  3. Muscle spasms (muscle contraction)
  4. Oedema peripheral (superficial swelling)
  5. Pain in extremity
  6. Psychological trauma
  7. Vasoconstriction (constriction of blood vessels, which increases blood pressure)
  8. Asthma
  9. Chest pain
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Arrhythmia (irregular heartbeat)
  4. Arthralgia (joint pain)
  5. Asthma
  6. Back pain
  7. Chest pain
  8. Dry mouth
  9. Dyspnoea exertional (breathlessness or shortness of breath)
  10. Exostosis (formation of new bone on the surface of a bone)

What are the existing conditions these people have? *

  1. Breast Cancer Metastatic: 17 people, 56.67%
  2. Metastatic Neoplasm (spreadable cancer tumour): 16 people, 53.33%
  3. Hypersensitivity: 13 people, 43.33%
  4. Diabetes: 12 people, 40.00%
  5. Pain: 6 people, 20.00%
  6. Breast Cancer Female: 5 people, 16.67%
  7. Metastases To Bone (cancer spreads to bone): 3 people, 10.00%
  8. High Blood Cholesterol: 3 people, 10.00%
  9. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 6.67%
  10. Insomnia (sleeplessness): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Nolvadex:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nolvadex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nolvadex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and tamoxifen citrate (the active ingredients of Lexapro and Nolvadex, respectively), and Lexapro and Nolvadex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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