Lexiva and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexiva (fosamprenavir calcium) and Acetaminophen (acetaminophen). Common drug interactions include anhedonia among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Lexiva and Acetaminophen. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Lexiva?

Lexiva has active ingredients of fosamprenavir calcium. It is often used in hiv infection. eHealthMe is studying from 1,408 Lexiva users. Check the latest studies of Lexiva.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 08, 2026

16 people who take Lexiva and Acetaminophen together, and have interactions are studied.

Lexiva and Acetaminophen drug interactions.

What are the common drug interactions of Lexiva and Acetaminophen, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Bone density decreased
Osteopenia (a condition where bone mineral density is lower than normal)
Proteinuria (presence of protein in the urine)
Back pain

male:

Emotional distress
Chronic kidney disease
Depression
Ankle fracture
Blood creatinine increased
Foot fracture
Nocturia (the need to get up in the night to urinate)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Renal cyst (kidney cyst)

What are the common drug interactions of Lexiva and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Fatigue (feeling of tiredness)
Renal failure (kidney dysfunction)
Ankle fracture
Back pain
Bone density decreased
Chronic kidney disease
Depression

50-59:

Chronic kidney disease
Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Renal impairment (severely reduced kidney function)
Depression
Multiple fractures
Nocturia (the need to get up in the night to urinate)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

60+:

Osteonecrosis (death of bone)
Anxiety
Osteoporotic fracture (fracture due to weak bone)
Thoracic vertebral fracture
Tooth loss
Bone density decreased
Bone loss
Dental necrosis (tissue inside a tooth dies)
Depression
Drug ineffective

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 12.50%
Asthma: 2 people, 12.50%
Urination - Excessive Volume: 1 person, 6.25%
Urinary Tract Inflammation: 1 person, 6.25%
Stress And Anxiety: 1 person, 6.25%
Rashes (redness): 1 person, 6.25%
Osteoporosis (bones weak and more likely to break): 1 person, 6.25%
Nausea (feeling of having an urge to vomit): 1 person, 6.25%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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