Librium and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Librium (chlordiazepoxide hydrochloride) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include type 2 diabetes mellitus among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Librium and Adderall. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.



On Jul, 10, 2026

24 people who take Librium and Adderall together, and have interactions are studied.

Librium and Adderall drug interactions.

What are the common drug interactions of Librium and Adderall, by gender? *:

female:

  1. Type 2 diabetes mellitus
  2. Vision blurred
  3. Visual impairment
  4. Vomiting
  5. Weight decreased
  6. Weight increased
  7. Drug ineffective
  8. Hallucination (an experience involving the perception of something not present)
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Back pain
  3. Low density lipoprotein increased (cholesterol increased in blood)
  4. Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
  5. Partner stress
  6. Sedation
  7. Weight increased
  8. Abnormal dreams
  9. Acetabulum fracture (socket of the hip joint- fracture)
  10. Blood cholesterol increased

What are the common drug interactions of Librium and Adderall, by age (0-1 to 60+)? *:

0-1:

  1. Aortic valve disease mixed
  2. Cardiac murmur (an heart sound in valve abnormality)
  3. Deafness
  4. Developmental delay
  5. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  6. Hypertrophic cardiomyopathy (a condition in which the heart muscle becomes abnormally thick)
  7. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  8. Pectus carinatum (pigeon chest, is a deformity of the chest)

2-9:

n/a

10-19:

  1. Sudden death

20-29:

  1. Bipolar disorder (mood disorder)
  2. Decreased appetite
  3. Drug abuse
  4. Mania (a state of abnormally elevated or irritable mood)
  5. Overdose
  6. Panic attack
  7. Suicide attempt
  8. Weight decreased

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Chronic kidney disease
  3. Emotional distress
  4. Pain
  5. Renal failure (kidney dysfunction)
  6. Partner stress

40-49:

  1. Abdominal pain upper
  2. Affect lability (emotional incontinence)
  3. Arthralgia (joint pain)
  4. Coagulopathy (blood's ability to clot is impaired)
  5. Constipation
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Diarrhoea
  8. Disturbance in attention
  9. Drug dependence
  10. Drug ineffective

50-59:

  1. Agitation (state of anxiety or nervous excitement)
  2. Bladder neck suspension
  3. Bradycardia (abnormally slow heart action)
  4. Depressed mood
  5. Drug ineffective
  6. Fall
  7. Foot fracture
  8. Hospitalisation
  9. Hypersensitivity
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

  1. Back pain
  2. Acetabulum fracture (socket of the hip joint- fracture)
  3. Insomnia (sleeplessness)
  4. Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
  5. Mean cell volume increased (more than normal average red blood cell volume)
  6. Mean platelet volume decreased (less than normal average size of platelet cells in blood)
  7. Red blood cell abnormality (abnormal red blood cells)
  8. Urinary retention (the inability to completely or partially empty the bladder)
  9. Blood cholesterol increased
  10. Blood potassium decreased

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 29.17%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 29.17%
  3. Hiv Infection: 3 people, 12.50%
  4. Sedation: 2 people, 8.33%
  5. Pain: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Librium and Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Librium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Librium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chlordiazepoxide hydrochloride and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Librium and Adderall, respectively), and Librium and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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