Lisinopril and Subutex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lisinopril (lisinopril) and Subutex (buprenorphine hydrochloride). Common drug interactions include drug withdrawal syndrome neonatal among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Lisinopril and Subutex. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.

What is Subutex?

Subutex has active ingredients of buprenorphine hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 8,763 Subutex users. Check the latest studies of Subutex.

On Jul, 19, 2026

42 people who take Lisinopril and Subutex together, and have interactions are studied.

Lisinopril and Subutex drug interactions.

What are the common drug interactions of Lisinopril and Subutex, by gender? *:

female:

Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
Erythema (redness of the skin)
Nausea (feeling of having an urge to vomit)
Abdominal discomfort
Abdominal distension
Amniotic infection syndrome of blane
Arthropathy
Ascites (accumulation of fluid in the abdominal cavity)
Butterfly rash
Coeliac disease (simple food intolerance)

male:

Asthenia (weakness)
Confusional state
Myalgia (muscle pain)
Stress
Vomiting
Cardiac disorder
Disturbance in attention
Epigastric discomfort
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)

What are the common drug interactions of Lisinopril and Subutex, by age (0-1 to 60+)? *:

0-1:

Apnoea (suspension of external breathing)
Crying
Developmental delay
Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Foetal hypokinesia (decreased bodily movement of foetus)
Tremor (trembling or shaking movements in one or more parts of your body)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthenia (weakness)
Infection susceptibility increased
Lower respiratory tract infection
Weight decreased
Abdominal discomfort
Injection site erythema (redness at injection site)
Injection site inflammation
Injection site mass
Injection site pain
Injection site pruritus (severe itching at injection site)

40-49:

Hallucination (an experience involving the perception of something not present)
Hyperkalaemia (damage to or disease of the kidney)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Lipase increased
Local swelling (swelling at the site of some application of substance or injury)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Oedema (fluid collection in tissue)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)

50-59:

Cardiac disorder
Confusional state
Disturbance in attention
Epigastric discomfort
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Abdominal distension
Ankylosing spondylitis (type of arthritis affecting the spine)
Anxiety
Cellulitis (infection under the skin)

60+:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Abdominal discomfort
Flushing (the warm, red condition of human skin)
Haemorrhage in pregnancy (bleeding in pregnancy)
Heart rate increased
Hyperkalaemia (damage to or disease of the kidney)
Hypoglycaemia neonatal (deficiency of glucose in the bloodstream in neonatal)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Increased appetite
Klinefelter's syndrome (a chromosomal abnormality (xxy)weaker muscles and reduced strength)

What are the existing conditions these people have? *

Drug Dependence: 11 people, 26.19%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 23.81%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 23.81%
High Blood Cholesterol: 7 people, 16.67%
Pain: 6 people, 14.29%
Stress And Anxiety: 3 people, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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