Lotemax and Nitrofurantoin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lotemax (loteprednol etabonate) and Nitrofurantoin (nitrofurantoin, macrocrystalline). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Lotemax and Nitrofurantoin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Lotemax?

Lotemax has active ingredients of loteprednol etabonate. It is often used in inflammation. eHealthMe is studying from 4,431 Lotemax users. Check the latest studies of Lotemax.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.



On Jul, 13, 2026

15 people who take Lotemax and Nitrofurantoin together, and have interactions are studied.

Lotemax and Nitrofurantoin drug interactions.

What are the common drug interactions of Lotemax and Nitrofurantoin, by gender? *:

female:

  1. Pain
  2. Anxiety
  3. Delirium (wild excitement)
  4. Delusion (a false belief or opinion)
  5. Fatigue (feeling of tiredness)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Hypotension (abnormally low blood pressure)
  8. Muscle spasms (muscle contraction)
  9. Nausea (feeling of having an urge to vomit)
  10. Pain in extremity

male:

n/a

What are the common drug interactions of Lotemax and Nitrofurantoin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Abdominal pain
  3. Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
  4. Anxiety
  5. Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
  6. Arthralgia (joint pain)
  7. Asthma
  8. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  9. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  10. Back pain

50-59:

  1. Blood glucose decreased
  2. Chest discomfort
  3. Culture urine positive
  4. Escherichia infection (bacterial infection by escherichia coli)
  5. Eye irritation
  6. Eyelids pruritus (eyelids itching)
  7. Ill-defined disorder
  8. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  9. Staphylococcal infection (an infection with staphylococcus bacteria)
  10. Urinary retention (the inability to completely or partially empty the bladder)

60+:

  1. Anxiety
  2. Pain
  3. Eye irritation
  4. Fatigue (feeling of tiredness)
  5. Hyperhidrosis (abnormally increased sweating)
  6. Hypertension (high blood pressure)
  7. Hypotension (abnormally low blood pressure)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Muscle spasms (muscle contraction)
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 7 people, 46.67%
  2. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 6.67%
  3. Pulmonary Congestion (congestion in the lungs): 1 person, 6.67%
  4. Impaired Gastric Emptying: 1 person, 6.67%
  5. Cough: 1 person, 6.67%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.67%
  7. Cardiac Failure Congestive: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Lotemax and Nitrofurantoin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lotemax and Nitrofurantoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lotemax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nitrofurantoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lotemax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrofurantoin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loteprednol etabonate and nitrofurantoin, macrocrystalline (the active ingredients of Lotemax and Nitrofurantoin, respectively), and Lotemax and Nitrofurantoin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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