Lupron and Gentamicin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lupron (leuprolide acetate) and Gentamicin (gentamicin sulfate). Common drug interactions include electrocardiogram qt prolonged among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Lupron and Gentamicin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.



On Jul, 20, 2026

15 people who take Lupron and Gentamicin together, and have interactions are studied.

Lupron and Gentamicin drug interactions.

What are the common drug interactions of Lupron and Gentamicin, by gender? *:

female:

  1. Electrocardiogram qt prolonged
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Fear of disease
  5. Gallbladder disorder
  6. Injury
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Pain
  9. Pulmonary embolism (blockage of the main artery of the lung)

male:

  1. Weight decreased
  2. Decreased appetite
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Chest pain
  5. Constipation
  6. Depression
  7. Dyspepsia (indigestion)
  8. Asthenia (weakness)
  9. Bone pain
  10. Breath sounds

What are the common drug interactions of Lupron and Gentamicin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Electrocardiogram qt prolonged

20-29:

n/a

30-39:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Fear of disease
  4. Gallbladder disorder
  5. Injury
  6. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  7. Pain
  8. Pulmonary embolism (blockage of the main artery of the lung)

40-49:

n/a

50-59:

  1. Anxiety
  2. Back pain
  3. Blood pressure increased
  4. Chest pain
  5. Constipation
  6. Depression
  7. Dyspepsia (indigestion)

60+:

  1. Weight decreased
  2. Decreased appetite
  3. Dehydration (dryness resulting from the removal of water)
  4. Delirium (wild excitement)
  5. Fall
  6. Fatigue (feeling of tiredness)
  7. General physical health deterioration (weak health status)
  8. Humerus fracture (injury to the upper arm bone)
  9. Hypokalaemia (low potassium)
  10. Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

  1. Prostate Cancer: 7 people, 46.67%
  2. Pain: 4 people, 26.67%
  3. Constipation: 3 people, 20.00%
  4. Headache (pain in head): 3 people, 20.00%
  5. Wax Blockage: 2 people, 13.33%
  6. Multiple Allergies (allergy to multiple agents): 2 people, 13.33%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 13.33%
  8. Asthma: 2 people, 13.33%
  9. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 13.33%
  10. Bladder Pain: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lupron and Gentamicin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gentamicin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lupron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gentamicin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate and gentamicin sulfate (the active ingredients of Lupron and Gentamicin, respectively), and Lupron and Gentamicin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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