Melphalan hydrochloride and Flonase drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Melphalan hydrochloride (melphalan hydrochloride) and Flonase (fluticasone propionate). Common drug interactions include angiopathy among females and febrile neutropenia among males.
The phase IV clinical study analyzes what interactions people have when they take Melphalan hydrochloride and Flonase. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Melphalan hydrochloride?
Melphalan hydrochloride has active ingredients of melphalan hydrochloride. eHealthMe is studying from 3,970 Melphalan hydrochloride users. Check the latest studies of Melphalan hydrochloride.
What is Flonase?
Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.
12 people who take Melphalan hydrochloride and Flonase together, and have interactions are studied.

What are the common drug interactions of Melphalan Hydrochloride and Flonase, by gender? *:
female:
- Angiopathy (generic term for a disease of the blood vessels)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Bacteraemia (presence of bacteria in the blood)
- Bone disorder
- Bone erosion
- Bone fragmentation
- Cardiac failure congestive
male:
- Febrile neutropenia (fever with reduced white blood cells)
- Mucosal inflammation (infection of mucous membrane)
- Oesophagitis (inflammation of oesophagus)
- Pneumonia
What are the common drug interactions of Melphalan Hydrochloride and Flonase, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Abdominal pain upper
- Actinomycosis (infection that causes sores, or abscesses)
- Anaemia (lack of blood)
- Angiopathy (generic term for a disease of the blood vessels)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Back pain
50-59:
- Abdominal pain upper
- Night sweats (sweating in night)
- Actinomycosis (infection that causes sores, or abscesses)
- Anaemia (lack of blood)
- Angiopathy (generic term for a disease of the blood vessels)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Bacteraemia (presence of bacteria in the blood)
60+:
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
- Renal failure (kidney dysfunction)
- Cholecystitis (infection of gallbladder)
- Febrile neutropenia (fever with reduced white blood cells)
- Mucosal inflammation (infection of mucous membrane)
- Multiple myeloma (cancer of the plasma cells)
- Oesophagitis (inflammation of oesophagus)
- Pneumonia
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 10 people, 83.33%
- High Blood Pressure: 9 people, 75.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 75.00%
- Fatigue (feeling of tiredness): 9 people, 75.00%
* Approximation only. Some reports may have incomplete information.
Do you take Melphalan hydrochloride and Flonase?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Melphalan hydrochloride (3,970 reports)
- Flonase (75,441 reports)
Browse all drug interactions of Melphalan hydrochloride and Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Melphalan hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Melphalan hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flonase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on melphalan hydrochloride and fluticasone propionate (the active ingredients of Melphalan hydrochloride and Flonase, respectively), and Melphalan hydrochloride and Flonase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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