Merrem and Ibuprofen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Merrem (meropenem) and Ibuprofen (ibuprofen). Common drug interactions include abdominal pain among females and cellulitis among males.
The phase IV clinical study analyzes what interactions people have when they take Merrem and Ibuprofen. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Merrem?
Merrem has active ingredients of meropenem. eHealthMe is studying from 996 Merrem users. Check the latest studies of Merrem.
What is Ibuprofen?
Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.
15 people who take Merrem and Ibuprofen together, and have interactions are studied.

What are the common drug interactions of Merrem and Ibuprofen, by gender? *:
female:
- Abdominal pain
- Acute respiratory failure
- Anaemia (lack of blood)
- Anxiety
- Blood pressure fluctuation
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dementia (madness)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
male:
- Cellulitis (infection under the skin)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Erythema (redness of the skin)
- Extradural abscess (pus may gather between a patient's skull and his dura)
- Groin abscess (pus in groin)
- Intervertebral discitis (infection in the intervertebral disc space)
- Muscular weakness (muscle weakness)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Osteomyelitis (infection of bone)
- Pain in extremity
What are the common drug interactions of Merrem and Ibuprofen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Erythema (redness of the skin)
- Pyrexia (fever)
- Swelling
10-19:
- Taste disturbance
20-29:
n/a
30-39:
n/a
40-49:
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Pneumonia
- Septic shock (shock due to blood infection)
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
50-59:
- Cellulitis (infection under the skin)
- Sepsis (a severe blood infection that can lead to organ failure and death)
60+:
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Abscess (pus)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Fungal infection
- General physical health deterioration (weak health status)
- Groin abscess (pus in groin)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Hyperosmolar state (life-threatening emergency manifested by marked elevation of blood glucose)
- Hypertension (high blood pressure)
- Hypotension (abnormally low blood pressure)
What are the existing conditions these people have? *
- High Blood Pressure: 6 people, 40.00%
- Constipation: 5 people, 33.33%
- Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 4 people, 26.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 26.67%
- Urinary Tract Infection: 4 people, 26.67%
- Hypokalemia (low potassium): 4 people, 26.67%
- Depression: 3 people, 20.00%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 20.00%
- Oedema Peripheral (superficial swelling): 3 people, 20.00%
- Pressure Ulcer: 3 people, 20.00%
* Approximation only. Some reports may have incomplete information.
Do you take Merrem and Ibuprofen?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Merrem and Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Merrem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Merrem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibuprofen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Erden M, Gulcan E, Bilen A, Bilen Y, Uyanik A, Keles M, "Pancytopen? a and Seps? s due to Meropenem: A Case Report", Tropical Journal of Pharmaceutical Research, 2013 Jan .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Erden M, Gulcan E, Bilen A, Bilen Y, Uyanik A, Keles M, "Pancytopen? a and Seps? s due to Meropenem: A Case Report", Tropical Journal of Pharmaceutical Research, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on meropenem and ibuprofen (the active ingredients of Merrem and Ibuprofen, respectively), and Merrem and Ibuprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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