Mesalamine and Buscopan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesalamine (mesalamine) and Buscopan (hyoscine butylbromide). Common drug interactions include general physical health deterioration among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Mesalamine and Buscopan. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.



On Jul, 26, 2026

27 people who take Mesalamine and Buscopan together, and have interactions are studied.

Mesalamine and Buscopan drug interactions.

What are the common drug interactions of Mesalamine and Buscopan, by gender? *:

female:

  1. General physical health deterioration (weak health status)
  2. Haematochezia (passage of stools containing blood)
  3. Drug ineffective
  4. Night sweats (sweating in night)
  5. Venous thrombosis (blood clot (thrombus) that forms within a vein)
  6. Blood pressure diastolic increased
  7. Chest discomfort
  8. Dizziness
  9. Head discomfort
  10. Pain in jaw

male:

  1. Abdominal discomfort
  2. Abdominal pain upper
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Decreased appetite
  5. Diarrhoea
  6. Dry eye (lack of adequate tears)
  7. Dry skin
  8. Dry throat
  9. Dysgeusia (disorder of the sense of taste)
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the common drug interactions of Mesalamine and Buscopan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Night sweats (sweating in night)
  2. Venous thrombosis (blood clot (thrombus) that forms within a vein)
  3. Abdominal pain lower
  4. General physical health deterioration (weak health status)
  5. Haematochezia (passage of stools containing blood)
  6. Diarrhoea
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Local swelling (swelling at the site of some application of substance or injury)
  9. Pain in extremity

50-59:

  1. Abdominal pain upper
  2. Asthenia (weakness)
  3. Asthma
  4. Bone pain
  5. Bronchial secretion retention
  6. Burn oesophageal (burn in the oesophagus)
  7. Chest pain
  8. Chills (felling of cold)
  9. Constipation
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

60+:

  1. Blood pressure diastolic increased
  2. Chest discomfort
  3. Dizziness
  4. General physical health deterioration (weak health status)
  5. Haematochezia (passage of stools containing blood)
  6. Head discomfort
  7. Pain in jaw
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

  1. Oral Candidiasis (fungal infection of mouth): 9 people, 33.33%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 18.52%
  3. Episcleritis (acute inflammatory disorder of the episclera of eye): 4 people, 14.81%

* Approximation only. Some reports may have incomplete information.

Do you take Mesalamine and Buscopan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mesalamine and Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mesalamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Buscopan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mesalamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buscopan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and hyoscine butylbromide (the active ingredients of Mesalamine and Buscopan, respectively), and Mesalamine and Buscopan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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