Methimazole and Naproxen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methimazole (methimazole) and Naproxen (naproxen). Common drug interactions include fracture among females and renal impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Methimazole and Naproxen. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Methimazole?

Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

On Jul, 19, 2026

44 people who take Methimazole and Naproxen together, and have interactions are studied.

Methimazole and Naproxen drug interactions.

What are the common drug interactions of Methimazole and Naproxen, by gender? *:

female:

Fracture
Fungal infection
Gallbladder oedema (swelling of gallbladder)
Gastritis (inflammation of stomach)
Headache (pain in head)
Heart rate increased
Hepatic cyst
Hepatitis (inflammation of the liver)
Hepatitis acute
Hospitalisation

male:

Renal impairment (severely reduced kidney function)
Asthenia (weakness)
Renal failure (kidney dysfunction)
Respiratory tract congestion (blockage on respiratory system)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Skin infection
Weight decreased
Arthralgia (joint pain)
Dizziness
Headache (pain in head)

What are the common drug interactions of Methimazole and Naproxen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hospitalisation

20-29:

Balance disorder
Blood pressure increased
Eye swelling
Heart rate increased
Oropharyngeal pain
Rhinorrhoea (watery mucus discharge from the nose)
Weight increased

30-39:

Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Periorbital oedema (swelling around the eyes)

40-49:

Ankle fracture
Anxiety
Back disorder
Blood pressure increased
Bone density decreased
Depression
Drug administration error
Dry mouth
Emotional distress
Epstein-barr virus infection

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Depression
Emotional distress
Joint swelling
Local swelling (swelling at the site of some application of substance or injury)
Nasopharyngitis (inflammation of the nasopharynx)
Renal impairment (severely reduced kidney function)

60+:

Weight decreased
Asthenia (weakness)
Lung disorder (lung disease)
Obstruction
Parkinson's disease
Renal impairment (severely reduced kidney function)
Respiratory tract congestion (blockage on respiratory system)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Dizziness
Headache (pain in head)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 15.91%
Osteoporosis (bones weak and more likely to break): 4 people, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 9.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.82%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 6.82%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.82%
Depression: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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