Methylcobalamin and Multivitamin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylcobalamin (vitamin b12) and Multivitamin (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include fatigue among females and chills among males.

The phase IV clinical study analyzes what interactions people have when they take Methylcobalamin and Multivitamin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Methylcobalamin?

Methylcobalamin has active ingredients of vitamin b12. It is often used in vitamin b12 deficiency. eHealthMe is studying from 3,184 Methylcobalamin users. Check the latest studies of Methylcobalamin.

What is Multivitamin?

Multivitamin has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 83,597 Multivitamin users. Check the latest studies of Multivitamin.



On Jul, 11, 2026

20 people who take Methylcobalamin and Multivitamin together, and have interactions are studied.

Methylcobalamin and Multivitamin drug interactions.

What are the common drug interactions of Methylcobalamin and Multivitamin, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Muscle spasms (muscle contraction)
  4. Administration site pain
  5. Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Anaemia (lack of blood)
  8. Anxiety
  9. Aphasia (damage to the parts of the brain that control language)
  10. Arrhythmia (irregular heartbeat)

male:

  1. Chills (felling of cold)
  2. Depression
  3. Fatigue (feeling of tiredness)
  4. Pain
  5. Pyrexia (fever)

What are the common drug interactions of Methylcobalamin and Multivitamin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Anxiety
  4. Aphasia (damage to the parts of the brain that control language)
  5. Bruxism (habitual grinding of the teeth, typically during sleep)
  6. Confusional state
  7. Crying
  8. Dyspepsia (indigestion)
  9. Dyspnoea (difficult or laboured respiration)
  10. Dysstasia (difficulty in standing)

30-39:

n/a

40-49:

  1. Bradycardia (abnormally slow heart action)
  2. Dizziness

50-59:

n/a

60+:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Weight decreased
  3. Fatigue (feeling of tiredness)
  4. Fear
  5. Full blood count decreased
  6. Haematochezia (passage of stools containing blood)
  7. Haemoglobin decreased
  8. Hallucination, visual (seeing things that aren't there)
  9. Hypersensitivity
  10. Insomnia (sleeplessness)

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 15.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 15.00%
  3. Pain: 3 people, 15.00%
  4. Swelling: 2 people, 10.00%
  5. Tinnitus (a ringing in the ears): 1 person, 5.00%
  6. Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 1 person, 5.00%
  7. High Blood Pressure: 1 person, 5.00%
  8. Herpes Simplex (herpes simplex is a common viral infection): 1 person, 5.00%
  9. Hallucinations (sensations that appear real but are created by your mind): 1 person, 5.00%
  10. General Symptom: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Methylcobalamin and Multivitamin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Methylcobalamin and Multivitamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylcobalamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Multivitamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methylcobalamin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multivitamin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vitamin b12 and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Methylcobalamin and Multivitamin, respectively), and Methylcobalamin and Multivitamin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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