Methylphenidate hydrochloride and Epinephrine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylphenidate hydrochloride (methylphenidate hydrochloride) and Epinephrine (epinephrine). Common drug interactions include pain in extremity among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Methylphenidate hydrochloride and Epinephrine. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Methylphenidate hydrochloride?

Methylphenidate hydrochloride has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 6,822 Methylphenidate hydrochloride users. Check the latest studies of Methylphenidate hydrochloride.

What is Epinephrine?

Epinephrine has active ingredients of epinephrine. It is often used in asthma. eHealthMe is studying from 21,290 Epinephrine users. Check the latest studies of Epinephrine.

On Jul, 19, 2026

31 people who take Methylphenidate hydrochloride and Epinephrine together, and have interactions are studied.

Methylphenidate hydrochloride and Epinephrine drug interactions.

What are the common drug interactions of Methylphenidate Hydrochloride and Epinephrine, by gender? *:

female:

Pain in extremity
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Staphylococcal infection (an infection with staphylococcus bacteria)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tooth infection
Tooth injury
Urinary tract infection
Vomiting

male:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Nasopharyngitis (inflammation of the nasopharynx)
Viral infection
Bordetella infection (upper respiratory infection caused by the bordetella)
Chest discomfort
Croup infectious (a loud cough that resembles the barking of a seal and difficulty breathing can transfer to other)
Ear infection
Ear pain
Headache (pain in head)

What are the common drug interactions of Methylphenidate Hydrochloride and Epinephrine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Croup infectious (a loud cough that resembles the barking of a seal and difficulty breathing can transfer to other)
Ear infection
Ear pain
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Pneumonia
Sinusitis (inflammation of sinus)

10-19:

Drug ineffective
Hyperglycaemia (high blood sugar)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Overdose
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Bone tuberculosis
Cardiac murmur (an heart sound in valve abnormality)
Diarrhoea

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Back pain
Blood urine present
Bone pain
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Dehydration (dryness resulting from the removal of water)
Facial pain
Fungal infection
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Headache (pain in head)

50-59:

Blood pressure increased
Arthralgia (joint pain)
Blood pressure fluctuation
Body temperature decreased
Body temperature fluctuation
Heart rate decreased
Heart rate increased
Lower respiratory tract infection
Nasopharyngitis (inflammation of the nasopharynx)
Viral infection

60+:

Nasopharyngitis (inflammation of the nasopharynx)
Abdominal pain
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gingivitis (inflammation of gums)
Headache (pain in head)
Infected cyst
Localised infection (infection at the single location)
Pain
Pain in extremity
Pneumonia

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 13 people, 41.94%
Primary Immunodeficiency Syndrome: 2 people, 6.45%
Idiopathic Urticaria (allergic reactions, presence of hives with unknown cause): 2 people, 6.45%
Hypotension (abnormally low blood pressure): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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