Micafungin and Tpn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Micafungin (micafungin sodium) and Tpn (niacinamide; pyridoxine hydrochloride; tyrosine). Common drug interactions include pneumonia among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Micafungin and Tpn. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Micafungin?

Micafungin has active ingredients of micafungin sodium. eHealthMe is studying from 6,562 Micafungin users. Check the latest studies of Micafungin.

What is Tpn?

Tpn has active ingredients of niacinamide; pyridoxine hydrochloride; tyrosine. eHealthMe is studying from 1,581 Tpn users. Check the latest studies of Tpn.



On Jul, 15, 2026

39 people who take Micafungin and Tpn together, and have interactions are studied.

Micafungin and Tpn drug interactions.

What are the common drug interactions of Micafungin and Tpn, by gender? *:

female:

  1. Pneumonia
  2. Pulmonary toxicity (side effects on the lungs)
  3. Sinusitis (inflammation of sinus)
  4. Weight decreased
  5. Hypotension (abnormally low blood pressure)
  6. Abdominal abscess (collection of pus in abdomen)
  7. Abdominal pain
  8. Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
  9. Appetite disorder (abnormal eating habits)
  10. Asthenia (weakness)

male:

  1. Cardiac failure
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. C-reactive protein increased
  4. Cystitis (inflammation of the wall of the bladder)
  5. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  6. Decreased appetite
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Encephalopathy (functioning of the brain is affected by some agent or condition)
  9. Enterocutaneous fistula
  10. Hospitalisation

What are the common drug interactions of Micafungin and Tpn, by age (0-1 to 60+)? *:

0-1:

  1. Hepatitis (inflammation of the liver)

2-9:

  1. Renal failure (kidney dysfunction)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)

10-19:

  1. Periorbital oedema (swelling around the eyes)
  2. Peripheral swelling
  3. Pulmonary oedema (fluid accumulation in the lungs)
  4. Pyrexia (fever)
  5. Renal impairment (severely reduced kidney function)
  6. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  7. Sedation
  8. Serum ferritin increased
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Swelling

20-29:

  1. Anaemia (lack of blood)
  2. Atelectasis (partial or complete collapse of the lung)
  3. Blood bilirubin increased
  4. Nausea (feeling of having an urge to vomit)
  5. Pleural effusion (water on the lungs)
  6. Pyrexia (fever)
  7. Renal haemorrhage (bleeding from kidney)
  8. Renal impairment (severely reduced kidney function)
  9. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  10. Vomiting

30-39:

  1. Anaemia (lack of blood)
  2. Aspartate aminotransferase increased
  3. Blood alkaline phosphatase increased
  4. Device dislocation
  5. Haemodynamic instability (disturbances in the blood movement in our body)
  6. Haemoglobin decreased
  7. Klebsiella infection
  8. Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Thrombocytopenia (decrease of platelets in blood)

40-49:

  1. Small intestinal obstruction (blockage in small intestine)
  2. C-reactive protein increased
  3. Enterocutaneous fistula
  4. Staphylococcal bacteraemia (a bacterial infection of blood)

50-59:

  1. Acute respiratory distress syndrome
  2. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  3. Alanine aminotransferase increased
  4. Aphasia (damage to the parts of the brain that control language)
  5. Aspartate aminotransferase increased
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Encephalopathy (functioning of the brain is affected by some agent or condition)
  10. Hypotension (abnormally low blood pressure)

60+:

  1. Cardiac failure
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fall
  5. Fatigue (feeling of tiredness)
  6. Haematoma (collection of blood outside the blood vessels)
  7. Insomnia (sleeplessness)
  8. Localised infection (infection at the single location)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pain

What are the existing conditions these people have? *

  1. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 10 people, 25.64%
  2. Flatulence (flatus expelled through the anus): 10 people, 25.64%
  3. Nausea (feeling of having an urge to vomit): 10 people, 25.64%
  4. Pain: 10 people, 25.64%
  5. Pneumonia: 8 people, 20.51%
  6. Hypokalemia (low potassium): 8 people, 20.51%
  7. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 7 people, 17.95%
  8. Insomnia (sleeplessness): 7 people, 17.95%
  9. Itching: 7 people, 17.95%
  10. High Blood Pressure: 7 people, 17.95%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Micafungin and Tpn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Micafungin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tpn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Micafungin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tpn and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on micafungin sodium and niacinamide; pyridoxine hydrochloride; tyrosine (the active ingredients of Micafungin and Tpn, respectively), and Micafungin and Tpn (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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