Mirtazapine and Cevimeline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mirtazapine (mirtazapine) and Cevimeline (cevimeline hydrochloride). Common drug interactions include diarrhoea among females and blood creatine phosphokinase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Mirtazapine and Cevimeline. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Mirtazapine?

Mirtazapine has active ingredients of mirtazapine. It is often used in depression. eHealthMe is studying from 82,120 Mirtazapine users. Check the latest studies of Mirtazapine.

What is Cevimeline?

Cevimeline has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,480 Cevimeline users. Check the latest studies of Cevimeline.



On Jul, 07, 2026

35 people who take Mirtazapine and Cevimeline together, and have interactions are studied.

Mirtazapine and Cevimeline drug interactions.

What are the common drug interactions of Mirtazapine and Cevimeline, by gender? *:

female:

  1. Diarrhoea
  2. Asthenia (weakness)
  3. Nausea (feeling of having an urge to vomit)
  4. Upper respiratory tract congestion
  5. Alopecia (absence of hair from areas of the body)
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Influenza like illness
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Myalgia (muscle pain)

male:

  1. Blood creatine phosphokinase increased
  2. Blood potassium decreased
  3. Weight decreased
  4. Arthralgia (joint pain)
  5. Diarrhoea
  6. Drug effect decreased
  7. Dyspnoea (difficult or laboured respiration)
  8. Gastric disorder (disease of stomach)
  9. Hospitalisation
  10. Pneumonia

What are the common drug interactions of Mirtazapine and Cevimeline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Blood creatine phosphokinase increased
  2. Blood potassium decreased

60+:

  1. Arthralgia (joint pain)
  2. Diarrhoea
  3. Dehydration (dryness resulting from the removal of water)
  4. Dizziness
  5. Dysphonia (speech disorder attributable to a disorder of phonation)
  6. Enterobiasis (intestinal infection caused by the parasitic roundworm called enterobius vermicularis)
  7. Erythema (redness of the skin)
  8. Fall
  9. Fatigue (feeling of tiredness)
  10. Feeling cold

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 10 people, 28.57%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 25.71%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 22.86%
  4. Hiv Infection: 7 people, 20.00%
  5. Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.71%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.71%
  7. Drowsiness: 2 people, 5.71%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Mirtazapine and Cevimeline?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mirtazapine and Cevimeline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mirtazapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cevimeline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirtazapine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cevimeline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mirtazapine and cevimeline hydrochloride (the active ingredients of Mirtazapine and Cevimeline, respectively), and Mirtazapine and Cevimeline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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