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Morphine and Sodium oxybate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Sodium oxybate (gamma - hydroxybutyrate (ghb)). Common drug interactions include coma among females and overdose among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Sodium oxybate. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

What is Sodium oxybate?

Sodium oxybate has active ingredients of gamma - hydroxybutyrate (ghb). eHealthMe is studying from 486 Sodium oxybate users. Check the latest studies of Sodium oxybate.

On Jul, 19, 2026

13 people who take Morphine and Sodium oxybate together, and have interactions are studied.

Morphine and Sodium oxybate drug interactions.

What are the common drug interactions of Morphine and Sodium Oxybate, by gender? *:

female:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Drug abuse
  3. Intentional self-injury

male:

  1. Overdose
  2. Drug abuse
  3. Substance abuse
  4. Adverse drug reaction
  5. Death
  6. Poisoning
  7. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Morphine and Sodium Oxybate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Overdose
  2. Drug abuse
  3. Substance abuse
  4. Adverse drug reaction
  5. Coma (state of unconsciousness lasting more than six hours)
  6. Death
  7. Intentional self-injury
  8. Poisoning
  9. Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Drug Abuse: 3 people, 23.08%
  2. Intentional Self-Injury: 2 people, 15.38%
  3. Painful Erection: 1 person, 7.69%
  4. Alcoholism (problems with alcohol): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine and Sodium oxybate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sodium oxybate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sodium oxybate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and gamma - hydroxybutyrate (ghb) (the active ingredients of Morphine and Sodium oxybate, respectively), and Morphine and Sodium oxybate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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