Motrin and Desogen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Motrin (ibuprofen) and Desogen (desogestrel; ethinyl estradiol). Common drug interactions include pickwickian syndrome among females and biliary dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Motrin and Desogen. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

What is Desogen?

Desogen has active ingredients of desogestrel; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 664 Desogen users. Check the latest studies of Desogen.

On Jul, 19, 2026

12 people who take Motrin and Desogen together, and have interactions are studied.

What are the common drug interactions of Motrin and Desogen, by gender? *:

female:

Pickwickian syndrome (extreme obesity accompanied by sleepiness, hypoventilation, and polycythemia)
Dizziness
Papilloedema (optic disc swelling)
Psychotic disorder
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hepatic steatosis (fatty liver disease)
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)

male:

Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Drug ineffective
Gallbladder disorder

What are the common drug interactions of Motrin and Desogen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pickwickian syndrome (extreme obesity accompanied by sleepiness, hypoventilation, and polycythemia)
Dizziness
Papilloedema (optic disc swelling)
Psychotic disorder
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hepatic steatosis (fatty liver disease)
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Somnolence (a state of near-sleep, a strong desire for sleep)
Splenomegaly (enlargement of spleen)

20-29:

Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Vomiting

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 7 people, 58.33%
Inflammation: 6 people, 50.00%
Acne (skin problems that cause pimples): 6 people, 50.00%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 8.33%
Premenstrual Syndrome: 1 person, 8.33%
Heavy Or Prolong Menstrual Bleeding: 1 person, 8.33%
Chest Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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