Myleran and Dexamethasone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Myleran (busulfan) and Dexamethasone (dexamethasone). Common drug interactions include stevens-johnson syndrome among females and abdominal pain among males.
The phase IV clinical study analyzes what interactions people have when they take Myleran and Dexamethasone. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Myleran?
Myleran has active ingredients of busulfan. eHealthMe is studying from 504 Myleran users. Check the latest studies of Myleran.
What is Dexamethasone?
Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.
12 people who take Myleran and Dexamethasone together, and have interactions are studied.

What are the common drug interactions of Myleran and Dexamethasone, by gender? *:
female:
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
- Gastroenteritis (inflammation of stomach and intestine)
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Mucosal inflammation (infection of mucous membrane)
- Pneumonia
- Pyrexia (fever)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
male:
- Abdominal pain
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Upper respiratory tract infection
- Diarrhoea
- Dizziness
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Haemorrhage (bleeding)
- Mucosal erosion (peeling off of mucous membrane)
- Mucosal inflammation (infection of mucous membrane)
What are the common drug interactions of Myleran and Dexamethasone, by age (0-1 to 60+)? *:
0-1:
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
2-9:
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Haemorrhage (bleeding)
- Mucosal erosion (peeling off of mucous membrane)
- Mucosal inflammation (infection of mucous membrane)
- Skin ulcer
- Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Upper respiratory tract infection
10-19:
n/a
20-29:
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
30-39:
n/a
40-49:
n/a
50-59:
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Rash erythematous (redness of the skin)
- Abdominal pain
- Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
- Diarrhoea
- Dizziness
- Erythema (redness of the skin)
- Overdose
60+:
n/a
What are the existing conditions these people have? *
- Hypokalemia (low potassium): 5 people, 41.67%
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 5 people, 41.67%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 41.67%
- Anaesthesia: 5 people, 41.67%
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 5 people, 41.67%
- Dyspnea (difficult or laboured breathing): 5 people, 41.67%
- Fungal Infection: 5 people, 41.67%
- Heart Disease: 5 people, 41.67%
- Hyperglycemia (high blood sugar): 5 people, 41.67%
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 5 people, 41.67%
* Approximation only. Some reports may have incomplete information.
Do you take Myleran and Dexamethasone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Myleran (504 reports)
- Dexamethasone (161,927 reports)
Browse all drug interactions of Myleran and Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Myleran:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dexamethasone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Myleran and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexamethasone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on busulfan and dexamethasone (the active ingredients of Myleran and Dexamethasone, respectively), and Myleran and Dexamethasone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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