Naproxen and Augmentin '125' drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Augmentin '125' (amoxicillin; clavulanate potassium). Common drug interactions include anxiety among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Augmentin '125'. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Augmentin '125'?

Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users. Check the latest studies of Augmentin '125'.

On Jul, 07, 2026

96 people who take Naproxen and Augmentin '125' together, and have interactions are studied.

Naproxen and Augmentin '125' drug interactions.

What are the common drug interactions of Naproxen and Augmentin '125', by gender? *:

female:

Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Pain in extremity
Cardiomegaly (increased size of heart than normal)
Pleural effusion (water on the lungs)
Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Vomiting
Atelectasis (partial or complete collapse of the lung)

male:

Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)
Diarrhoea
Injury
Oedema peripheral (superficial swelling)
Osteonecrosis of jaw (death of bone of jaw)
Vomiting
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Depression

What are the common drug interactions of Naproxen and Augmentin '125', by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Agitation (state of anxiety or nervous excitement)
Abnormal behaviour
Aggression
Anger
Drug ineffective
Emotional disorder
Euphoric mood (excessively happy but may become angry or irritable)
Hostility
Impulsive behaviour
Irritability

20-29:

Abdominal pain upper
Blood cholesterol increased
Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Nausea (feeling of having an urge to vomit)
Vomiting
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cholecystitis (infection of gallbladder)

30-39:

Abdominal hernia
Abdominal pain
Accident at work
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Decreased appetite
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphonia (speech disorder attributable to a disorder of phonation)

40-49:

Emotional distress
Oedema peripheral (superficial swelling)
Diarrhoea
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting
Anaemia postoperative
Angiopathy (generic term for a disease of the blood vessels)
Arthralgia (joint pain)
Blindness

50-59:

Abdominal pain
Cellulitis (infection under the skin)
Chills (felling of cold)
Decreased appetite
Diarrhoea
Erectile dysfunction
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Oedema peripheral (superficial swelling)
Pain in extremity

60+:

Dyspnoea (difficult or laboured respiration)
Diarrhoea
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Inflammation
Multiple myeloma (cancer of the plasma cells)
Neuralgia (pain in one or more nerves)
Oedema (fluid collection in tissue)
Osteonecrosis of jaw (death of bone of jaw)
Spinal osteoarthritis (joint cartilage loss in spine)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 8 people, 8.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 7.29%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 7.29%
Depression: 6 people, 6.25%
Birth Control: 6 people, 6.25%
Stress And Anxiety: 5 people, 5.21%
Multiple Myeloma (cancer of the plasma cells): 5 people, 5.21%
Migraine (headache): 5 people, 5.21%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.21%
Acute Kidney Failure: 5 people, 5.21%

* Approximation only. Some reports may have incomplete information.

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