Nexavar and Lexapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nexavar (sorafenib tosylate) and Lexapro (escitalopram oxalate). Common drug interactions include pleural effusion among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Nexavar and Lexapro. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Nexavar?

Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 23,250 Nexavar users. Check the latest studies of Nexavar.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

On Jul, 09, 2026

82 people who take Nexavar and Lexapro together, and have interactions are studied.

What are the common drug interactions of Nexavar and Lexapro, by gender? *:

female:

Pleural effusion (water on the lungs)
Abdominal pain
Muscle spasms (muscle contraction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Constipation
Dyspnoea (difficult or laboured respiration)
Haematuria (presence of blood in urine)
Hypoaesthesia (reduced sense of touch or sensation)

male:

Rash
Diarrhoea
Vomiting
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Pain in extremity
Speech disorder
Blood glucose increased
Blood pressure increased

What are the common drug interactions of Nexavar and Lexapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chills (felling of cold)
Decreased appetite
Hyperkeratosis (thickening of the outer layer of the skin)
Oral pain
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash pruritic (redness with itching)
Gait disturbance
Pain in extremity
Diarrhoea

40-49:

Abdominal hernia
Abdominal pain
Adnexa uteri cyst (ovarian cysts)
Anaemia of malignant disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Back pain
Blood triglycerides increased
Cardiomegaly (increased size of heart than normal)

50-59:

Headache (pain in head)
Pain
Chest pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Constipation
Decreased appetite
Dental caries
Hypoaesthesia (reduced sense of touch or sensation)
Injury
Pyrexia (fever)

60+:

Rash
Fatigue (feeling of tiredness)
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Blood potassium decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Dehydration (dryness resulting from the removal of water)
Dry skin
Dysphonia (speech disorder attributable to a disorder of phonation)

What are the existing conditions these people have? *

Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 21 people, 25.61%
Metastases To Bone (cancer spreads to bone): 11 people, 13.41%
Hepatic Neoplasm Malignant (liver cancer): 8 people, 9.76%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 7 people, 8.54%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

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