Niaspan and Drisdol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Niaspan (niacin) and Drisdol (ergocalciferol). Common drug interactions include atrial fibrillation among females and lactic acidosis among males.

The phase IV clinical study analyzes what interactions people have when they take Niaspan and Drisdol. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

What is Drisdol?

Drisdol has active ingredients of ergocalciferol. It is often used in vitamin d. eHealthMe is studying from 1,740 Drisdol users. Check the latest studies of Drisdol.



On Jul, 10, 2026

14 people who take Niaspan and Drisdol together, and have interactions are studied.

Niaspan and Drisdol drug interactions.

What are the common drug interactions of Niaspan and Drisdol, by gender? *:

female:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Drug ineffective
  4. Glaucoma (increased fluid pressure in the eye with vision loss)
  5. Hepatic steatosis (fatty liver disease)
  6. Hypertriglyceridaemia (excess of triglycerides in the blood)
  7. Insulin resistance
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Thyroid neoplasm (tumour of thyroid)
  10. Weight increased

male:

  1. Lactic acidosis (low ph in body tissues)
  2. Paraganglion neoplasm (paraganglion tumour)
  3. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  5. Pneumonia
  6. Lung infection
  7. Cardiac failure congestive
  8. Dehydration (dryness resulting from the removal of water)
  9. Drug ineffective
  10. General physical health deterioration (weak health status)

What are the common drug interactions of Niaspan and Drisdol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Colitis (inflammation of colon)

40-49:

n/a

50-59:

  1. Lactic acidosis (low ph in body tissues)
  2. Paraganglion neoplasm (paraganglion tumour)
  3. Lung infection
  4. Pneumonia
  5. Chronic kidney disease
  6. Drug ineffective
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Nephrogenic anaemia (anaemia due to kidney disease)

60+:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Thyroid neoplasm (tumour of thyroid)
  3. Metastases to peritoneum (cancer spreads to peritoneum)
  4. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  5. Ovarian cancer metastatic (cancer of ovary spreads to other organ or parts)
  6. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
  7. Pneumonia
  8. Ascites (accumulation of fluid in the abdominal cavity)
  9. Cardiac failure congestive
  10. Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

  1. Pain: 7 people, 50.00%
  2. Agitation (state of anxiety or nervous excitement): 4 people, 28.57%
  3. Multiple Myeloma (cancer of the plasma cells): 4 people, 28.57%
  4. Constipation: 4 people, 28.57%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 28.57%
  6. Nausea And Vomiting: 4 people, 28.57%
  7. Hypersensitivity: 4 people, 28.57%
  8. High Blood Pressure: 3 people, 21.43%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 21.43%
  10. Type 2 Diabetes: 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Niaspan and Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Niaspan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Drisdol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Niaspan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Drisdol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on niacin and ergocalciferol (the active ingredients of Niaspan and Drisdol, respectively), and Niaspan and Drisdol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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