Nicotine and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nicotine (nicotine) and Vancomycin (vancomycin). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Nicotine and Vancomycin. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

On Jul, 10, 2026

82 people who take Nicotine and Vancomycin together, and have interactions are studied.

Nicotine and Vancomycin drug interactions.

What are the common drug interactions of Nicotine and Vancomycin, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Respiratory failure (inadequate gas exchange by the respiratory system)
Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Renal injury (kidney injury)
Abscess (pus)
Abscess limb (limb infection)

male:

Chronic kidney disease
Mucosal inflammation (infection of mucous membrane)
Fatigue (feeling of tiredness)
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries))
Rash
Hyperkalaemia (damage to or disease of the kidney)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Hypotension (abnormally low blood pressure)
Nephrogenic anaemia (anaemia due to kidney disease)
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Nicotine and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Mucosal inflammation (infection of mucous membrane)
Fatigue (feeling of tiredness)
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries))
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

20-29:

Leukopenia (less number of white blood cells in blood)
Erythema (redness of the skin)
Hypersensitivity
Hypoaesthesia (reduced sense of touch or sensation)
Lip swelling
Respiration (transport of oxygen from the outside air to the cells within tissues)

30-39:

Renal failure (kidney dysfunction)
Chronic kidney disease
Renal injury (kidney injury)
Pain
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abscess limb (limb infection)
Bone density decreased
Emotional distress
Groin abscess (pus in groin)

40-49:

Cellulitis (infection under the skin)
Subcutaneous abscess
Abscess limb (limb infection)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Liver abscess (pus in liver)
Malignant neoplasm progression (cancer tumour came back)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Pancreatic carcinoma (pancreatic cancer)
Urinary tract infection
Abscess (pus)

50-59:

Aspartate aminotransferase increased
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug hypersensitivity
Genital abscess (build up of pus in genital)
Hemiparesis (weakness on one side of the body)
Hypoxia (low oxygen in tissues)
Leukocytosis (increased white blood cells)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

60+:

Hypotension (abnormally low blood pressure)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Anaemia (lack of blood)
Chronic kidney disease
Disease progression
Fall

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 27 people, 32.93%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 17 people, 20.73%
Depression: 16 people, 19.51%
High Blood Pressure: 16 people, 19.51%
Hypotension (abnormally low blood pressure): 15 people, 18.29%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 13 people, 15.85%
Rickets (softening of bones): 13 people, 15.85%
Diarrhea: 13 people, 15.85%
Type 2 Diabetes: 12 people, 14.63%
Sepsis (a severe blood infection that can lead to organ failure and death): 11 people, 13.41%

* Approximation only. Some reports may have incomplete information.

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