Nolvadex and Hydroxyzine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nolvadex (tamoxifen citrate) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include actinomycosis among females.
The phase IV clinical study analyzes what interactions people have when they take Nolvadex and Hydroxyzine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Nolvadex?
Nolvadex has active ingredients of tamoxifen citrate. It is often used in breast cancer. eHealthMe is studying from 5,506 Nolvadex users. Check the latest studies of Nolvadex.
What is Hydroxyzine?
Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.
17 people who take Nolvadex and Hydroxyzine together, and have interactions are studied.

What are the common drug interactions of Nolvadex and Hydroxyzine, by gender? *:
female:
- Actinomycosis (infection that causes sores, or abscesses)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Gingival swelling (gums swelling)
- Hyperplasia (enlargement of an organ or tissue)
- Hypoaesthesia (reduced sense of touch or sensation)
- Impaired healing
- Inflammation
- Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
- Oral discomfort (pain or irritation in mouth)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
male:
n/a
What are the common drug interactions of Nolvadex and Hydroxyzine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Actinomycosis (infection that causes sores, or abscesses)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Gingival swelling (gums swelling)
- Hyperplasia (enlargement of an organ or tissue)
- Hypoaesthesia (reduced sense of touch or sensation)
- Impaired healing
- Inflammation
- Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
- Oral discomfort (pain or irritation in mouth)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 17 people, 100.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 94.12%
- Bone Pain: 16 people, 94.12%
- Breast Cancer Metastatic: 6 people, 35.29%
- Colon Cancer: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Nolvadex (5,506 reports)
- Hydroxyzine (54,069 reports)
Browse all drug interactions of Nolvadex and Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nolvadex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nolvadex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyzine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- K?rm?z?bekmez H, Yesiltepe Mutlu RG, Dursun F, ??güven ?P, "Tamoxifen-associated hirsutism: an unusual side effect in a 5-year-old girl with McCune-Albright syndrome", Journal of Pediatric Endocrinology and Metabolism, 2015 Sep .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- K?rm?z?bekmez H, Yesiltepe Mutlu RG, Dursun F, ??güven ?P, "Tamoxifen-associated hirsutism: an unusual side effect in a 5-year-old girl with McCune-Albright syndrome", Journal of Pediatric Endocrinology and Metabolism, 2015 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on tamoxifen citrate and hydroxyzine hydrochloride (the active ingredients of Nolvadex and Hydroxyzine, respectively), and Nolvadex and Hydroxyzine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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