Novantrone and Nolvadex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Novantrone (mitoxantrone hydrochloride) and Nolvadex (tamoxifen citrate). Common drug interactions include inflammation among females.

The phase IV clinical study analyzes what interactions people have when they take Novantrone and Nolvadex. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Novantrone?

Novantrone has active ingredients of mitoxantrone hydrochloride. It is often used in multiple sclerosis. eHealthMe is studying from 3,349 Novantrone users. Check the latest studies of Novantrone.

What is Nolvadex?

Nolvadex has active ingredients of tamoxifen citrate. It is often used in breast cancer. eHealthMe is studying from 5,506 Nolvadex users. Check the latest studies of Nolvadex.

On Aug, 06, 2026

26 people who take Novantrone and Nolvadex together, and have interactions are studied.

Novantrone and Nolvadex drug interactions.

What are the common drug interactions of Novantrone and Nolvadex, by gender? *:

female:

Inflammation
Pyrexia (fever)
Gingival oedema (swelling of gums)
Hot flush (sudden feelings of heat)
Hypertension (high blood pressure)
Klebsiella infection
Libido decreased (loss of interest in sex)
Malaise (a feeling of general discomfort or uneasiness)
Morganella infection (infection by morganella morganii bacteria)
Oral discharge

male:

n/a

What are the common drug interactions of Novantrone and Nolvadex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Actinomycosis (infection that causes sores, or abscesses)
Adenoma benign (non-cancerous tumour -secreting)
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Apical granuloma (tumour of the apex of a nonvital tooth)
Atelectasis (partial or complete collapse of the lung)
Atrophic vulvovaginitis (inflammation of the vulva)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)

40-49:

Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
Sinus congestion (blockage of sinus)
Sinus headache (headache caused by sinus infections)
Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
Lower extremity mass (mass in lower legs)
Oedema peripheral (superficial swelling)
Osteopenia (a condition where bone mineral density is lower than normal)
Ovarian failure (ovary is not functioning)
Visual impairment
Ligament sprain (ligament stretched)

50-59:

Acute leukaemia (blood cancer)
Asthenia (weakness)
Diarrhoea
Headache (pain in head)
Inflammation
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Purpura (purplish discoloration of the skin)
Rigors (an episode of shaking or exaggerated shivering)
Sweating increased (excess sweating)
Sweet's syndrome (a skin disease characterized by the sudden onset of fever)

60+:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Acute leukaemia (blood cancer)
Pyrexia (fever)
Weight decreased
White blood cell count decreased
Asthenia (weakness)
Leukaemia (blood or bone marrow cancer)
Epistaxis (bleed from the nose)
Haemoglobin decreased
Haemolytic anaemia (anaemia due to haemolysis)

What are the existing conditions these people have? *

Chronic Thyroiditis (long lasting inflammation of thyroid gland): 19 people, 73.08%
Stress And Anxiety: 17 people, 65.38%
Metastases To Bone (cancer spreads to bone): 13 people, 50.00%

* Approximation only. Some reports may have incomplete information.

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