Omeprazole and Lokelma drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omeprazole (omeprazole) and Lokelma (sodium zirconium cyclosilicate). Common drug interactions include aspartate aminotransferase increased among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Omeprazole and Lokelma. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

What is Lokelma?

Lokelma has active ingredients of sodium zirconium cyclosilicate. eHealthMe is studying from 1,678 Lokelma users. Check the latest studies of Lokelma.

On Jul, 26, 2026

44 people who take Omeprazole and Lokelma together, and have interactions are studied.

Omeprazole and Lokelma drug interactions.

What are the common drug interactions of Omeprazole and Lokelma, by gender? *:

female:

Aspartate aminotransferase increased
Asthenia (weakness)
Back pain
Blood creatinine increased
Blood potassium increased
Blood pressure increased
Breast pain
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cardiac arrest
Cardiac failure congestive

male:

Death
Renal failure (kidney dysfunction)
Dysphagia (a condition in which swallowing is difficult or painful)
Hyperchloraemia (an excess of chlorides in the blood)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Infection
Nephrogenic anaemia (anaemia due to kidney disease)
Neutropenia (an abnormally low number of neutrophils)
Pain
Plasma cell myeloma (cancer that begins in plasma cells)

What are the common drug interactions of Omeprazole and Lokelma, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Ascites (accumulation of fluid in the abdominal cavity)
Dyspnoea (difficult or laboured respiration)
Abdominal pain
Abdominal pain upper
Back pain
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Confusional state
Decreased appetite
Drug dependence
Drug ineffective

30-39:

n/a

40-49:

Abdominal pain upper
Blood pressure increased
Chest discomfort
Death
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Hypersensitivity
Infusion site haemorrhage (bleeding from infusion site)
Infusion site pain

50-59:

Chronic kidney disease
Anaemia (lack of blood)
Asthenia (weakness)
Bone density decreased
Death
Emotional distress
Pain
Renal failure (kidney dysfunction)
Tooth fracture
Tooth loss

60+:

Death
Asthenia (weakness)
Chronic kidney disease
Hyperchloraemia (an excess of chlorides in the blood)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Infection
Nephrogenic anaemia (anaemia due to kidney disease)
Neutropenia (an abnormally low number of neutrophils)
Plasma cell myeloma (cancer that begins in plasma cells)
Pneumonia

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 10 people, 22.73%
Stress And Anxiety: 6 people, 13.64%
High Blood Pressure: 5 people, 11.36%
Cystic Fibrosis (disease of the secretary glands): 4 people, 9.09%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 9.09%
Muscle Spasms (muscle contraction): 3 people, 6.82%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.82%
Itching: 3 people, 6.82%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.82%
High Blood Cholesterol: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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