Oramorph sr and Acetaminophen and codeine phosphate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oramorph sr (morphine sulfate) and Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate). Common drug interactions include cellulitis among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Oramorph sr and Acetaminophen and codeine phosphate. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Oramorph sr?

Oramorph sr has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 2,897 Oramorph sr users. Check the latest studies of Oramorph sr.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.



On Aug, 01, 2026

20 people who take Oramorph sr and Acetaminophen and codeine phosphate together, and have interactions are studied.

Oramorph sr and Acetaminophen and codeine phosphate drug interactions.

What are the common drug interactions of Oramorph Sr and Acetaminophen And Codeine Phosphate, by gender? *:

female:

  1. Cellulitis (infection under the skin)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Diarrhoea
  4. Tooth infection
  5. Abdominal pain
  6. Arthralgia (joint pain)
  7. Ascites (accumulation of fluid in the abdominal cavity)
  8. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  9. Fatigue (feeling of tiredness)
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

male:

  1. Vomiting
  2. Anaesthesia
  3. Cardiac arrest
  4. Chest pain
  5. Diarrhoea
  6. Dysuria (painful or difficult urination)
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Muscular weakness (muscle weakness)
  9. Peripheral ischaemia (impaired circulation to an extremity)
  10. Peroneal nerve palsy

What are the common drug interactions of Oramorph Sr and Acetaminophen And Codeine Phosphate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Device related infection
  2. Diarrhoea
  3. Infection
  4. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  5. Anaesthesia
  6. Dysuria (painful or difficult urination)
  7. Muscular weakness (muscle weakness)
  8. Peroneal nerve palsy

50-59:

  1. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  2. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  3. Abdominal discomfort
  4. Chest pain
  5. Dehydration (dryness resulting from the removal of water)
  6. Diarrhoea
  7. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  8. Interstitial lung disease
  9. Pleural effusion (water on the lungs)
  10. Pyrexia (fever)

60+:

  1. Cellulitis (infection under the skin)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Neoplasm malignant (cancer tumour)
  4. Peripheral ischaemia (impaired circulation to an extremity)
  5. Vomiting
  6. Tooth infection
  7. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  8. Haemoglobin decreased
  9. Osteomyelitis (infection of bone)
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Breast Cancer: 5 people, 25.00%
  2. Constipation: 5 people, 25.00%
  3. Depression: 5 people, 25.00%
  4. Nausea (feeling of having an urge to vomit): 5 people, 25.00%
  5. Indigestion: 3 people, 15.00%
  6. High Blood Pressure: 3 people, 15.00%
  7. Insomnia (sleeplessness): 3 people, 15.00%
  8. Hypercalcaemia (elevated calcium (ca+) level in the blood): 2 people, 10.00%
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 10.00%
  10. Bone Disorder: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oramorph sr and Acetaminophen and codeine phosphate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oramorph sr and Acetaminophen and codeine phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oramorph sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acetaminophen and codeine phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oramorph sr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetaminophen and codeine phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and acetaminophen; codeine phosphate (the active ingredients of Oramorph sr and Acetaminophen and codeine phosphate, respectively), and Oramorph sr and Acetaminophen and codeine phosphate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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