Oxycodone and Cardene drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Cardene (nicardipine hydrochloride). Common drug interactions include renal failure among females and abscess limb among males.
The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Cardene. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Oxycodone?
Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.
What is Cardene?
Cardene has active ingredients of nicardipine hydrochloride. eHealthMe is studying from 729 Cardene users. Check the latest studies of Cardene.
16 people who take Oxycodone and Cardene together, and have interactions are studied.

What are the common drug interactions of Oxycodone and Cardene, by gender? *:
female:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bone disorder
- Bone pain
- Contusion (a type of hematoma of tissue in which capillaries)
- Drug ineffective
- Feeling hot
- Fibromyalgia (a long-term condition which causes pain all over the body)
male:
- Abscess limb (limb infection)
- Chronic kidney disease
- Thrombosis (formation of a blood clot inside a blood vessel)
- Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
- Cerebral haemorrhage (bleeding within the brain)
- Confusional state
- Disease complication
- Headache (pain in head)
- Hydrocephalus (water on the brain)
- Post-traumatic stress disorder
What are the common drug interactions of Oxycodone and Cardene, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Chronic kidney disease
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
40-49:
- Exostosis (formation of new bone on the surface of a bone)
- Tendon rupture (tear of tendon)
- Thrombosis (formation of a blood clot inside a blood vessel)
50-59:
- Abscess limb (limb infection)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bone disorder
- Bone pain
- Contusion (a type of hematoma of tissue in which capillaries)
- Drug ineffective
- Feeling hot
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Hip fracture
60+:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Injury
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure acute (rapid kidney dysfunction)
- Unresponsive to stimuli
- Vomiting
- Subdural haematoma (blood collects between the skull and the surface of the brain)
- Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
What are the existing conditions these people have? *
- Sleep Disorder: 4 people, 25.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 25.00%
- High Blood Pressure: 4 people, 25.00%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 18.75%
- Weight Decreased: 2 people, 12.50%
- Hypotension (abnormally low blood pressure): 2 people, 12.50%
- Bipolar Disorder (mood disorder): 2 people, 12.50%
- Blood Glucose Decreased: 2 people, 12.50%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 12.50%
- Diabetes: 2 people, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Oxycodone and Cardene?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Oxycodone and Cardene:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Oxycodone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cardene:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxycodone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cardene and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on oxycodone hydrochloride and nicardipine hydrochloride (the active ingredients of Oxycodone and Cardene, respectively), and Oxycodone and Cardene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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