Pemetrexed and Fenofibrate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pemetrexed (pemetrexed) and Fenofibrate (fenofibrate). Common drug interactions include gastric ulcer haemorrhage among females and microangiopathic haemolytic anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Pemetrexed and Fenofibrate. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Pemetrexed?
Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.
What is Fenofibrate?
Fenofibrate has active ingredients of fenofibrate. It is often used in high blood cholesterol. eHealthMe is studying from 40,456 Fenofibrate users. Check the latest studies of Fenofibrate.
44 people who take Pemetrexed and Fenofibrate together, and have interactions are studied.

What are the common drug interactions of Pemetrexed and Fenofibrate, by gender? *:
female:
- Gastric ulcer haemorrhage (bleeding ulcer of stomach)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Dyspnoea (difficult or laboured respiration)
- Lip swelling
- Local swelling (swelling at the site of some application of substance or injury)
- Road traffic accident
- Swollen tongue (swelling of tongue)
- General physical condition
- Hypersensitivity
- Respiratory tract oedema (swelling of respiratory tract due to excess fluid collection in tissue)
male:
- Microangiopathic haemolytic anaemia (anaemia due to inability of bone marrow to compensate the premature destruction of red blood cells)
- Depressed level of consciousness
- Respiratory distress (difficulty in breathing)
- Asthenia (weakness)
- Blood creatinine increased
- Dehydration (dryness resulting from the removal of water)
- Gout (uric acid crystals building up in the body)
- Hemiparesis (weakness on one side of the body)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Hypotension (abnormally low blood pressure)
What are the common drug interactions of Pemetrexed and Fenofibrate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
50-59:
- Microangiopathic haemolytic anaemia (anaemia due to inability of bone marrow to compensate the premature destruction of red blood cells)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Anaemia (lack of blood)
- Gout (uric acid crystals building up in the body)
- Leukocytosis (increased white blood cells)
60+:
- Gastric ulcer haemorrhage (bleeding ulcer of stomach)
- Depressed level of consciousness
- Local swelling (swelling at the site of some application of substance or injury)
- Peripheral swelling
- Respiratory distress (difficulty in breathing)
- Road traffic accident
- Swollen tongue (swelling of tongue)
- Asthenia (weakness)
- Blood creatinine increased
- Dehydration (dryness resulting from the removal of water)
What are the existing conditions these people have? *
- Lung Adenocarcinoma (a form of non-small cell lung cancer): 19 people, 43.18%
- Lung Cancer - Non-Small Cell (lung cancer): 11 people, 25.00%
- High Blood Pressure: 10 people, 22.73%
- Type 2 Diabetes: 8 people, 18.18%
- Stress And Anxiety: 6 people, 13.64%
- Pain: 5 people, 11.36%
- Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 5 people, 11.36%
- Nausea (feeling of having an urge to vomit): 5 people, 11.36%
- Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 9.09%
- Non-Small Cell Lung Cancer Stage Iv: 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Pemetrexed and Fenofibrate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pemetrexed (17,491 reports)
- Fenofibrate (40,456 reports)
Browse all drug interactions of Pemetrexed and Fenofibrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pemetrexed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fenofibrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pemetrexed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fenofibrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on pemetrexed and fenofibrate (the active ingredients of Pemetrexed and Fenofibrate, respectively), and Pemetrexed and Fenofibrate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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