Phoslo and Ultram drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Phoslo (calcium acetate) and Ultram (tramadol hydrochloride). Common drug interactions include cardiac failure congestive among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Phoslo and Ultram. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.
What is Phoslo?
Phoslo has active ingredients of calcium acetate. eHealthMe is studying from 4,291 Phoslo users. Check the latest studies of Phoslo.
What is Ultram?
Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.
69 people who take Phoslo and Ultram together, and have interactions are studied.

What are the common drug interactions of Phoslo and Ultram, by gender? *:
female:
- Cardiac failure congestive
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Arthralgia (joint pain)
- Back pain
- Catheter site haemorrhage (bleeding at catheter site)
- Confusional state
- Dementia (madness)
- Haemorrhage (bleeding)
- Hyperhidrosis (abnormally increased sweating)
- Hypertension (high blood pressure)
male:
- Dyspnoea (difficult or laboured respiration)
- Dizziness
- Back pain
- Blood pressure fluctuation
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
- Loss of consciousness
- Nausea (feeling of having an urge to vomit)
- Pallor
- Rash
What are the common drug interactions of Phoslo and Ultram, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Cardiomyopathy (weakening of the heart muscle)
- Epistaxis (bleed from the nose)
- Staphylococcal bacteraemia (a bacterial infection of blood)
- Arteriovenous fistula
- Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
- Bacteraemia (presence of bacteria in the blood)
- Haemorrhage (bleeding)
30-39:
- Back pain
- Blood pressure fluctuation
- Diarrhoea
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
- Loss of consciousness
- Pallor
40-49:
- Nausea (feeling of having an urge to vomit)
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Chills (felling of cold)
- Coagulopathy (blood's ability to clot is impaired)
- Confusional state
- Decreased appetite
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Hallucination, visual (seeing things that aren't there)
- Hypotension (abnormally low blood pressure)
50-59:
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Hyperhidrosis (abnormally increased sweating)
- Muscle spasms (muscle contraction)
- Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Abasia (inability to walk)
- Anaemia (lack of blood)
- Angiopathy (generic term for a disease of the blood vessels)
60+:
- Hypotension (abnormally low blood pressure)
- Confusional state
- Pyrexia (fever)
- Hallucination (an experience involving the perception of something not present)
- Insomnia (sleeplessness)
- Asthenia (weakness)
- Renal failure acute (rapid kidney dysfunction)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Arteriovenous fistula occlusion
What are the existing conditions these people have? *
- High Blood Pressure: 10 people, 14.49%
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 8 people, 11.59%
- Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 8 people, 11.59%
- Itching: 8 people, 11.59%
- Hypersensitivity: 8 people, 11.59%
- Indigestion: 7 people, 10.14%
- Neuropathy Peripheral (surface nerve damage): 6 people, 8.70%
- Headache (pain in head): 6 people, 8.70%
- Joint Pain: 5 people, 7.25%
- Constipation: 5 people, 7.25%
* Approximation only. Some reports may have incomplete information.
Do you take Phoslo and Ultram?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Phoslo and Ultram:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Phoslo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ultram:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Phoslo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ultram and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
- Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on calcium acetate and tramadol hydrochloride (the active ingredients of Phoslo and Ultram, respectively), and Phoslo and Ultram (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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