Plegridy and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plegridy (peginterferon beta-1a) and Premarin (estrogens, conjugated). Common drug interactions include back pain among females.

The phase IV clinical study analyzes what interactions people have when they take Plegridy and Premarin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Plegridy?

Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 13, 2026

14 people who take Plegridy and Premarin together, and have interactions are studied.

Plegridy and Premarin drug interactions.

What are the common drug interactions of Plegridy and Premarin, by gender? *:

female:

Back pain
Headache (pain in head)
Palpitations (feelings or sensations that your heart is pounding or racing)
Anaemia (lack of blood)
Arthralgia (joint pain)
Back injury
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Drug intolerance (drug sensitivity)
Eye allergy

male:

n/a

What are the common drug interactions of Plegridy and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Activities of daily living impaired
Anxiety
Fatigue (feeling of tiredness)
Fear
Influenza like illness
Mood swings (an extreme or rapid change in mood)
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Chest pain
Dry skin
Dyspnoea (difficult or laboured respiration)
Eye disorder
Eye irritation
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypertension (high blood pressure)
Influenza like illness

60+:

Anaemia (lack of blood)
Back injury
Gait disturbance
Hyperaesthesia
Influenza
Joint swelling
Mobility decreased (ability to move is reduced)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pain

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 85.71%
Back Pain: 2 people, 14.29%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.14%
Gait Disturbance: 1 person, 7.14%
Drowsiness: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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