Proamatine and Crestor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Proamatine (midodrine hydrochloride) and Crestor (rosuvastatin calcium). Common drug interactions include ascites among females and platelet count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Proamatine and Crestor. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,763 Crestor users. Check the latest studies of Crestor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

39 people who take Proamatine and Crestor together, and have interactions are studied.

Proamatine and Crestor drug interactions.

What are the common drug interactions of Proamatine and Crestor, by gender? *:

female:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Bladder neoplasm (bladder tumour)
  3. Blood bilirubin increased
  4. Blood oestrogen decreased
  5. Bowel movement irregularity
  6. Cervical vertebral fracture
  7. Confusional state
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Decreased appetite
  10. Diabetes mellitus inadequate control

male:

  1. Platelet count decreased
  2. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  3. Lymphoma (cancer that begins in immune system cells)
  4. Parkinson's disease
  5. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  6. Psychotic disorder
  7. Rash erythematous (redness of the skin)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Septic shock (shock due to blood infection)
  10. Activities of daily living impaired

What are the common drug interactions of Proamatine and Crestor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Postmenopausal haemorrhage (post-menopausal bleeding)
  2. Nausea (feeling of having an urge to vomit)
  3. Blood catecholamines increased
  4. Blood pressure increased
  5. Chest discomfort
  6. Dizziness
  7. Fatigue (feeling of tiredness)
  8. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  9. Oxygen saturation decreased
  10. Abdominal pain

60+:

  1. Confusional state
  2. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  3. Dyspnoea (difficult or laboured respiration)
  4. Exfoliative rash (scaly red generalized skin rash)
  5. Haematochezia (passage of stools containing blood)
  6. Haemorrhage (bleeding)
  7. Headache (pain in head)
  8. Kidney infection
  9. Loss of consciousness
  10. Lymphoma (cancer that begins in immune system cells)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 11 people, 28.21%
  2. Pain: 9 people, 23.08%
  3. Nausea (feeling of having an urge to vomit): 6 people, 15.38%
  4. Constipation: 5 people, 12.82%
  5. Stress And Anxiety: 4 people, 10.26%
  6. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 10.26%
  7. Insomnia (sleeplessness): 3 people, 7.69%
  8. Cardiac Disorder: 3 people, 7.69%
  9. Cervical Spinal Stenosis (narrowing of the spinal canal in the neck): 3 people, 7.69%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Proamatine and Crestor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Proamatine and Crestor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Proamatine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Crestor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Proamatine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Crestor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride and rosuvastatin calcium (the active ingredients of Proamatine and Crestor, respectively), and Proamatine and Crestor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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