Profen and Depo-provera drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Profen (ibuprofen) and Depo-provera (medroxyprogesterone acetate). Common drug interactions include pelvic pain among females and foetal exposure during pregnancy among males.
The phase IV clinical study analyzes what interactions people have when they take Profen and Depo-provera. It is created by eHealthMe based on reports of 414 people who take the same drugs from the FDA, and is updated regularly.
What is Profen?
Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.
What is Depo-provera?
Depo-provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 17,093 Depo-provera users. Check the latest studies of Depo-provera.
414 people who take Profen and Depo-provera together, and have interactions are studied.

What are the common drug interactions of Profen and Depo-provera, by gender? *
What are the common drug interactions of Profen and Depo-provera, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Profen and Depo-provera?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Profen (245,311 reports)
- Depo-provera (17,093 reports)
Browse all drug interactions of Profen and Depo-provera:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Profen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Depo-provera:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Profen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Depo-provera and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and medroxyprogesterone acetate (the active ingredients of Profen and Depo-provera, respectively), and Profen and Depo-provera (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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