Profen and Trichlormethiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Trichlormethiazide (trichlormethiazide). Common drug interactions include headache among females and completed suicide among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Trichlormethiazide. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Trichlormethiazide?

Trichlormethiazide has active ingredients of trichlormethiazide. eHealthMe is studying from 2,613 Trichlormethiazide users. Check the latest studies of Trichlormethiazide.

On Jul, 19, 2026

16 people who take Profen and Trichlormethiazide together, and have interactions are studied.

Profen and Trichlormethiazide drug interactions.

What are the common drug interactions of Profen and Trichlormethiazide, by gender? *:

female:

Headache (pain in head)
Hypersensitivity
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)
Neck pain
Oral herpes (viral infection of mouth)
Oral pain
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Sleep disorder

male:

Completed suicide (act of taking one's own life)
Cardiac arrest
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Death
Hypoglycaemia (deficiency of glucose in the bloodstream)
Poisoning

What are the common drug interactions of Profen and Trichlormethiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Completed suicide (act of taking one's own life)
Cardiac arrest
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Death
Poisoning

50-59:

n/a

60+:

Abdominal discomfort
Arthralgia (joint pain)
Oral herpes (viral infection of mouth)
Oral pain
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Sleep disorder
Swelling
Swollen tongue (swelling of tongue)
Tendon pain
Weight increased

What are the existing conditions these people have? *

Suicide Attempt: 5 people, 31.25%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.25%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and Trichlormethiazide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously