Renvela and Accupril drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Renvela (sevelamer carbonate) and Accupril (quinapril hydrochloride). Common drug interactions include pruritus among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Renvela and Accupril. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Renvela?
Renvela has active ingredients of sevelamer carbonate. eHealthMe is studying from 10,923 Renvela users. Check the latest studies of Renvela.
What is Accupril?
Accupril has active ingredients of quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,404 Accupril users. Check the latest studies of Accupril.
19 people who take Renvela and Accupril together, and have interactions are studied.

What are the common drug interactions of Renvela and Accupril, by gender? *:
female:
- Pruritus (severe itching of the skin)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Drug hypersensitivity
- Rash morbilliform (a rash that looks like measles)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Dry skin
- Joint range of motion decreased (disease of joint movement)
- Muscular weakness (muscle weakness)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
male:
- Anxiety
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Pruritus (severe itching of the skin)
- Rash
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Joint range of motion decreased (disease of joint movement)
- Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
- Clavicle fracture
- Delusional disorder, unspecified type
What are the common drug interactions of Renvela and Accupril, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Abdominal pain
- Cushingoid (obesity and weakening of the muscles)
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Granuloma (a small area of inflammation due to tissue injury)
- Growth retardation (delayed growth)
- Headache (pain in head)
- Injection site pain
- Malaise (a feeling of general discomfort or uneasiness)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Oedema peripheral (superficial swelling)
20-29:
n/a
30-39:
- Anxiety
- Depression
- Chronic kidney disease
- Clavicle fracture
- Delusional disorder, unspecified type
- Renal failure (kidney dysfunction)
- Tooth loss
- Night sweats (sweating in night)
- Asthenia (weakness)
- Blood creatinine increased
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
50-59:
- Nausea (feeling of having an urge to vomit)
- Abdominal discomfort
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Anxiety
- Blood phosphorus increased
- Bradycardia (abnormally slow heart action)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Chronic kidney disease
- Drug ineffective
- Loss of consciousness
60+:
- Dry skin
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Mobility decreased (ability to move is reduced)
- Muscular weakness (muscle weakness)
- Pneumonia
- Oedema peripheral (superficial swelling)
- Pain
What are the existing conditions these people have? *
- Nuclear Magnetic Resonance Imaging Brain: 6 people, 31.58%
- Hiv Infection: 3 people, 15.79%
- High Blood Cholesterol: 2 people, 10.53%
- Chronic Kidney Disease: 2 people, 10.53%
- Nausea (feeling of having an urge to vomit): 2 people, 10.53%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%
- Urination - Excessive Volume: 1 person, 5.26%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.26%
- Diabetes: 1 person, 5.26%
- Dyspnea (difficult or laboured breathing): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Renvela and Accupril?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Renvela and Accupril:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Renvela:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Accupril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Renvela and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Accupril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sevelamer carbonate and quinapril hydrochloride (the active ingredients of Renvela and Accupril, respectively), and Renvela and Accupril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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