Revlimid and Nitrofurantoin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Revlimid (lenalidomide) and Nitrofurantoin (nitrofurantoin, macrocrystalline). Common drug interactions include osteonecrosis among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Revlimid and Nitrofurantoin. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Revlimid?

Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 378,026 Revlimid users. Check the latest studies of Revlimid.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

On Jul, 12, 2026

53 people who take Revlimid and Nitrofurantoin together, and have interactions are studied.

Revlimid and Nitrofurantoin drug interactions.

What are the common drug interactions of Revlimid and Nitrofurantoin, by gender? *:

female:

Osteonecrosis (death of bone)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pruritus (severe itching of the skin)
White blood cell count decreased
Rash
C-reactive protein increased
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Diarrhoea

male:

Asthenia (weakness)
Osteonecrosis of jaw (death of bone of jaw)
Rib fracture
Spinal fracture (fracture in one of vertebrae)
Urinary tract obstruction
Anaemia (lack of blood)
Melaena (the passage of black, tarry stools)
Thrombocytopenia (decrease of platelets in blood)
Blood potassium decreased
Constipation

What are the common drug interactions of Revlimid and Nitrofurantoin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Disease progression
Febrile neutropenia (fever with reduced white blood cells)
Lymphoma (cancer that begins in immune system cells)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)

40-49:

n/a

50-59:

Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Drug ineffective
Infection
Myocarditis (inflammation of heart muscle myocardium)
Neuropathy peripheral (surface nerve damage)
Neutropenia (an abnormally low number of neutrophils)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

60+:

Pneumonia
Anaemia (lack of blood)
Arthralgia (joint pain)
Back pain
Bone disorder
Dental caries
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysphonia (speech disorder attributable to a disorder of phonation)
Facial pain
Groin pain

What are the existing conditions these people have? *

Pain: 20 people, 37.74%
Muscle Spasms (muscle contraction): 13 people, 24.53%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 7 people, 13.21%
Urinary Retention (the inability to completely or partially empty the bladder): 4 people, 7.55%
Depression: 4 people, 7.55%
Stress And Anxiety: 3 people, 5.66%
Sleep Disorder: 3 people, 5.66%
Lymphoma (cancer that begins in immune system cells): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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