Roxanol and Hydrocortisone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxanol (morphine sulfate) and Hydrocortisone (hydrocortisone). Common drug interactions include blood lactate dehydrogenase increased among females.

The phase IV clinical study analyzes what interactions people have when they take Roxanol and Hydrocortisone. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Roxanol?

Roxanol has active ingredients of morphine sulfate. eHealthMe is studying from 807 Roxanol users. Check the latest studies of Roxanol.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.



On Aug, 04, 2026

26 people who take Roxanol and Hydrocortisone together, and have interactions are studied.

Roxanol and Hydrocortisone drug interactions.

What are the common drug interactions of Roxanol and Hydrocortisone, by gender? *:

female:

  1. Blood lactate dehydrogenase increased
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Pain in extremity
  4. Pneumonia
  5. Renal cyst (kidney cyst)
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Neuropathy peripheral (surface nerve damage)
  10. Thyroid neoplasm (tumour of thyroid)

male:

n/a

What are the common drug interactions of Roxanol and Hydrocortisone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood lactate dehydrogenase increased
  2. Blood triglycerides increased
  3. Body temperature increased
  4. Bone disorder
  5. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  6. Bone pain
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Burning sensation
  9. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  10. Chills (felling of cold)

40-49:

n/a

50-59:

n/a

60+:

  1. Blood lactate dehydrogenase increased
  2. Anaemia (lack of blood)
  3. Cellulitis (infection under the skin)
  4. Culture urine positive
  5. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  6. Depression
  7. Disability
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Ear pain
  10. Escherichia infection (bacterial infection by escherichia coli)

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Roxanol and Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Roxanol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Roxanol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocortisone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and hydrocortisone (the active ingredients of Roxanol and Hydrocortisone, respectively), and Roxanol and Hydrocortisone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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