Roxicodone and Temaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxicodone (oxycodone hydrochloride) and Temaz (temazepam). Common drug interactions include dysphonia among females and drug dependence among males.

The phase IV clinical study analyzes what interactions people have when they take Roxicodone and Temaz. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.

What is Temaz?

Temaz has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,293 Temaz users. Check the latest studies of Temaz.



On Jul, 14, 2026

94 people who take Roxicodone and Temaz together, and have interactions are studied.

Roxicodone and Temaz drug interactions.

What are the common drug interactions of Roxicodone and Temaz, by gender? *:

female:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Facial pain
  3. Fall
  4. Groin pain
  5. Intervertebral disc disorder (spinal disc disorder)
  6. Leukopenia (less number of white blood cells in blood)
  7. Lumbar vertebral fracture
  8. Myalgia (muscle pain)
  9. Neurofibroma (non-cancerous tumours that grow on nerves throughout the body)
  10. Neuropathy peripheral (surface nerve damage)

male:

  1. Drug dependence
  2. Depression
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  4. Abnormal behaviour
  5. Aggression
  6. Alanine aminotransferase increased
  7. Aortic atherosclerosis (degenerative process of aortic arteries)
  8. Aspartate aminotransferase increased
  9. Atelectasis (partial or complete collapse of the lung)
  10. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)

What are the common drug interactions of Roxicodone and Temaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Completed suicide (act of taking one's own life)
  2. Dyspnoea (difficult or laboured respiration)
  3. Erythema (redness of the skin)
  4. Flushing (the warm, red condition of human skin)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Vasoconstriction (constriction of blood vessels, which increases blood pressure)

20-29:

  1. Type 1 diabetes mellitus

30-39:

  1. Overdose
  2. Depression
  3. Drug dependence
  4. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  5. Constipation
  6. Drug abuse
  7. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  8. Abnormal behaviour
  9. Aggression
  10. Aortic atherosclerosis (degenerative process of aortic arteries)

40-49:

  1. Completed suicide (act of taking one's own life)
  2. Death
  3. Chronic kidney disease
  4. Dyspnoea (difficult or laboured respiration)
  5. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  6. Renal failure (kidney dysfunction)
  7. Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
  8. Ventricular extrasystoles (premature cardiac contraction)
  9. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  10. Delusion (a false belief or opinion)

50-59:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
  4. Blood alkaline phosphatase increased
  5. Blood bilirubin increased
  6. Completed suicide (act of taking one's own life)
  7. Gamma-glutamyltransferase increased
  8. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  9. Pain in extremity
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

60+:

  1. Arthralgia (joint pain)
  2. Anxiety
  3. Fall
  4. Groin pain
  5. Injury
  6. Intervertebral disc disorder (spinal disc disorder)
  7. Leukopenia (less number of white blood cells in blood)
  8. Lumbar vertebral fracture
  9. Multiple myeloma (cancer of the plasma cells)
  10. Myalgia (muscle pain)

What are the existing conditions these people have? *

  1. Muscle Spasms (muscle contraction): 20 people, 21.28%
  2. Stress And Anxiety: 8 people, 8.51%
  3. Sleep Disorder: 6 people, 6.38%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 6.38%
  5. Constipation: 6 people, 6.38%
  6. Nausea (feeling of having an urge to vomit): 5 people, 5.32%
  7. High Blood Cholesterol: 5 people, 5.32%

* Approximation only. Some reports may have incomplete information.

Do you take Roxicodone and Temaz?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Roxicodone and Temaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Roxicodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Temaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Roxicodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Temaz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and temazepam (the active ingredients of Roxicodone and Temaz, respectively), and Roxicodone and Temaz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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