Rubraca and Nexium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rubraca (rucaparib camsylate) and Nexium (esomeprazole magnesium). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Rubraca and Nexium. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Rubraca?

Rubraca has active ingredients of rucaparib camsylate. eHealthMe is studying from 10,770 Rubraca users. Check the latest studies of Rubraca.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.



On Jul, 09, 2026

58 people who take Rubraca and Nexium together, and have interactions are studied.

Rubraca and Nexium drug interactions.

What are the common drug interactions of Rubraca and Nexium, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Dizziness
  4. Platelet count decreased
  5. Abdominal pain upper
  6. Blood magnesium decreased
  7. Muscle twitching
  8. Nightmare (unpleasant dream)
  9. Sleep disorder
  10. Vitamin b12 decreased

male:

n/a

What are the common drug interactions of Rubraca and Nexium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Neuropathy peripheral (surface nerve damage)
  2. Pain
  3. Pain in extremity
  4. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  5. Platelet count decreased
  6. Pruritus (severe itching of the skin)
  7. Diarrhoea
  8. Dysgeusia (disorder of the sense of taste)
  9. Dyspnoea (difficult or laboured respiration)
  10. Hot flush (sudden feelings of heat)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Constipation
  3. Nausea (feeling of having an urge to vomit)
  4. Malignant neoplasm progression (cancer tumour came back)
  5. Cough
  6. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  7. Dysgeusia (disorder of the sense of taste)
  8. Haemoglobin decreased
  9. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  10. Headache (pain in head)

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Muscle twitching
  4. Nightmare (unpleasant dream)
  5. Sleep disorder
  6. Vitamin b12 decreased
  7. Vitamin d decreased
  8. Abdominal pain upper
  9. Haematocrit decreased
  10. Haemoglobin decreased

What are the existing conditions these people have? *

  1. Ovarian Cancer (cancer of ovary): 56 people, 96.55%
  2. Stress And Anxiety: 8 people, 13.79%
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 5 people, 8.62%
  4. Pain: 5 people, 8.62%
  5. Sleep Disorder: 4 people, 6.90%
  6. Nausea (feeling of having an urge to vomit): 4 people, 6.90%
  7. Insomnia (sleeplessness): 4 people, 6.90%
  8. Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 3 people, 5.17%
  9. High Blood Pressure: 3 people, 5.17%
  10. Dyspnea (difficult or laboured breathing): 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

Do you take Rubraca and Nexium?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rubraca and Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rubraca:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rubraca and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on rucaparib camsylate and esomeprazole magnesium (the active ingredients of Rubraca and Nexium, respectively), and Rubraca and Nexium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: