Sectral and Neoral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sectral (acebutolol hydrochloride) and Neoral (cyclosporine). Common drug interactions include blood creatine phosphokinase increased among females and renal impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Sectral and Neoral. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Sectral?

Sectral has active ingredients of acebutolol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,548 Sectral users. Check the latest studies of Sectral.

What is Neoral?

Neoral has active ingredients of cyclosporine. It is often used in psoriasis. eHealthMe is studying from 26,084 Neoral users. Check the latest studies of Neoral.

On Jul, 08, 2026

59 people who take Sectral and Neoral together, and have interactions are studied.

What are the common drug interactions of Sectral and Neoral, by gender? *:

female:

Blood creatine phosphokinase increased
Chest pain
Confusional state
Depersonalisation
Diarrhoea
Drug exposure during pregnancy
Empyema (collection of pus in a cavity in the body)
Encephalitis (inflammation of the brain)
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Hallucination (an experience involving the perception of something not present)

male:

Renal impairment (severely reduced kidney function)
Renal failure (kidney dysfunction)
Cytomegalovirus infection
Duodenal ulcer
Thrombocytopenia (decrease of platelets in blood)
Abdominal pain upper
Cytolytic hepatitis (dissolution or destruction of a liver cell)
Gastric ulcer (stomach ulcer)
Gastritis (inflammation of stomach)
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Sectral and Neoral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Bradycardia neonatal (sinus rhythm with a heart rate below the normal limit in newborn)
Chest pain
Cyanosis neonatal (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails in newborn)
Drug exposure during pregnancy
Empyema (collection of pus in a cavity in the body)
Granulocytopenia neonatal (lack of granulocyte in neonate)
Hypothermia neonatal (body temperature drops below the required temperature for normal metabolism and body functions in newborn)
Malaise (a feeling of general discomfort or uneasiness)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Mycoplasma infection (bacterial infection)

10-19:

Agitation (state of anxiety or nervous excitement)
Allergy test positive
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Anuria (failure of the kidneys to produce urine)
Arteriovenous fistula thrombosis (formation of a blood clot inside a blood vessel-av fistula)
Central venous pressure decreased
Chills (felling of cold)
Circulatory collapse
Depressed level of consciousness
Drug hypersensitivity

20-29:

Anxiety
Depersonalisation
Hallucination, visual (seeing things that aren't there)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

30-39:

Anaemia (lack of blood)
Drug exposure during pregnancy

40-49:

Scotoma (an area of diminished vision within the visual field)
Visual acuity reduced (reduced clearness of vision)
Vomiting
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Ear infection
Granulocytes maturation arrest (not producing the mature granulocyte)
Headache (pain in head)
Migraine (headache)
Optic neuritis retrobulbar (a form of optic neuritis in which the optic nerve, which is at the back of the eye, becomes inflamed)
Pharyngitis (inflammation of the pharynx, causing a sore throat)

50-59:

Hepatitis acute
Nephropathy toxic (damage to kidney due to toxins)
Renal failure chronic (long lasting kidney dysfunction)
Renal impairment (severely reduced kidney function)
Angioedema (rapid swelling of the dermis)
Concomitant disease progression (progress in accompanying disease)
Osteoporosis (bones weak and more likely to break)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood creatinine increased

60+:

Renal impairment (severely reduced kidney function)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Gastritis (inflammation of stomach)
Abdominal distension
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Hepatic pain (pain in liver)
Oedema peripheral (superficial swelling)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 3 people, 5.08%
Hepatitis B: 3 people, 5.08%
Anaesthesia: 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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