Seroquel and Alli drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Alli (orlistat). Common drug interactions include cold sweat among females and type 2 diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Seroquel and Alli. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Alli?

Alli has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 22,818 Alli users. Check the latest studies of Alli.



On Jul, 19, 2026

40 people who take Seroquel and Alli together, and have interactions are studied.

Seroquel and Alli drug interactions.

What are the common drug interactions of Seroquel and Alli, by gender? *:

female:

  1. Cold sweat
  2. Diarrhoea
  3. Dizziness
  4. Drug administration error
  5. Drug exposure during pregnancy
  6. Dysarthria (speech disorder)
  7. Eating disorder
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Gastrointestinal pain
  10. Haematochezia (passage of stools containing blood)

male:

  1. Type 2 diabetes mellitus
  2. Blood cholesterol increased
  3. Abdominal pain upper
  4. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  5. Blood glucose increased
  6. Cardiac failure congestive
  7. Cystic fibrosis pancreatic (fibrosis with cyst in the pancreas)
  8. Dyspepsia (indigestion)
  9. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  10. Flatulence (flatus expelled through the anus)

What are the common drug interactions of Seroquel and Alli, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  2. Blood glucose increased
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  4. Hypoglycaemia (deficiency of glucose in the bloodstream)
  5. Pyrexia (fever)
  6. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  7. Speech disorder

20-29:

n/a

30-39:

  1. Blood triglycerides increased
  2. Cyst (a closed sac)
  3. Neoplasm (tumour)
  4. Neuropathy peripheral (surface nerve damage)
  5. Pancreatic cyst
  6. Renal cyst (kidney cyst)
  7. Splenic cyst (cyst on spleen or near by)
  8. Uterine disorder
  9. Type 2 diabetes mellitus
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

40-49:

  1. Type 2 diabetes mellitus
  2. Blood triglycerides increased
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Hyperglycaemia (high blood sugar)
  5. Weight increased
  6. Hysterectomy
  7. Neoplasm (tumour)
  8. Glycosuria (excretion of glucose into the urine)
  9. Upper limb fracture
  10. Blood cholesterol increased

50-59:

  1. Abdominal pain
  2. Anal haemorrhage
  3. Diarrhoea
  4. Eating disorder
  5. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  6. Gastrointestinal pain
  7. Haematochezia (passage of stools containing blood)
  8. Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  10. Kidney infection

60+:

  1. Hyperglycaemia (high blood sugar)
  2. Hypersomnia (excessive daytime sleepiness (eds))
  3. Hepatitis (inflammation of the liver)
  4. Infection
  5. Infrequent bowel movements
  6. Labyrinthitis (inflammation of the labyrinth or inner ear)
  7. Localised infection (infection at the single location)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Oral infection

What are the existing conditions these people have? *

  1. Depression: 9 people, 22.50%
  2. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 7.50%
  3. Weight Decreased: 2 people, 5.00%
  4. Stress And Anxiety: 2 people, 5.00%
  5. Pain: 2 people, 5.00%
  6. Nervousness: 2 people, 5.00%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.00%
  8. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 5.00%
  9. Constipation: 2 people, 5.00%
  10. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Seroquel and Alli:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Alli:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Seroquel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alli and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate and orlistat (the active ingredients of Seroquel and Alli, respectively), and Seroquel and Alli (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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